Association between preeclampsia and chronic kidney disease

Introduction: With a prevalence of 2-8%, preemclampsia constitutes a scenario that may imply the beginning of future vascular and metabolic alterations, among which we could mention chronic kidney disease. Objective: To establish preeclampsia as a factor associated with chronic kidney disease. Metho...

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Main Authors: Enrique Villarreal Ríos, Paulina Itzel López Bejarano, Liliana Galicia Rodríguez, Emma Rosa Vargas Daza, Lidia Martínez González, Ariosto Lugo Rodríguez
Format: Article
Language:Spanish
Published: Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires 2019-09-01
Series:Revista de Nefrología, Diálisis y Trasplante
Subjects:
Online Access:https://www.revistarenal.org.ar/index.php/rndt/article/view/463
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author Enrique Villarreal Ríos
Paulina Itzel López Bejarano
Liliana Galicia Rodríguez
Emma Rosa Vargas Daza
Lidia Martínez González
Ariosto Lugo Rodríguez
author_facet Enrique Villarreal Ríos
Paulina Itzel López Bejarano
Liliana Galicia Rodríguez
Emma Rosa Vargas Daza
Lidia Martínez González
Ariosto Lugo Rodríguez
author_sort Enrique Villarreal Ríos
collection DOAJ
description Introduction: With a prevalence of 2-8%, preemclampsia constitutes a scenario that may imply the beginning of future vascular and metabolic alterations, among which we could mention chronic kidney disease. Objective: To establish preeclampsia as a factor associated with chronic kidney disease. Methods: Case-control study covering women who had been pregnant. The population sample included 60 subjects in the case group and 40 in the control group. The case group included patients with chronic kidney disease (glomerular filtration rate lower than 60 ml/min/1.73m2, CKD-EPI formula); the control group included patients who did not suffer from chronic kidney disease. Preeclampsia diagnosis was established according to medical history. The statistical analysis comprised the chi-squared test (X2), odds ratio, logistic regression and event occurrence probability. Results: Among the chronic kidney disease patients, 80% reported a history of preeclampsia; 35% of subjects who did not suffer from chronic kidney disease also had a similar history (p=0.00). The time of evolution of preeclampsia and the diagnosis of chronic kidney disease was 7.5 years (95% CI: 7.10-7.89). The model which best explains chronic kidney disease includes preeclampsia and patient’s age (p=0.000), y=-3.444 + 1.794 (history of preeclampsia) + 0.082 (patient’s age). If the patient is 35 years old and has a history of preeclampsia, the probability of chronic kidney disease is 0.7721. Conclusion: Preeclampsia is a factor associated with chronic kidney disease.
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spelling doaj.art-fa945a8dbb0649e2bffdb118f7ed67892022-12-21T19:35:14ZspaAsociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos AiresRevista de Nefrología, Diálisis y Trasplante0326-34282346-85482019-09-01393184191401Association between preeclampsia and chronic kidney diseaseEnrique Villarreal Ríos0Paulina Itzel López Bejarano1Liliana Galicia Rodríguez2Emma Rosa Vargas Daza3Lidia Martínez González4Ariosto Lugo Rodríguez5Unidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaUnidad de Medicina Familiar N° 16 Dr. Arturo Guerrero Ortiz, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaServicio de Nefrología, Hospital General Regional N° 1 Querétaro, Instituto Mexicano del Seguro Social (IMSS), Querétaro, Querétaro ArteagaIntroduction: With a prevalence of 2-8%, preemclampsia constitutes a scenario that may imply the beginning of future vascular and metabolic alterations, among which we could mention chronic kidney disease. Objective: To establish preeclampsia as a factor associated with chronic kidney disease. Methods: Case-control study covering women who had been pregnant. The population sample included 60 subjects in the case group and 40 in the control group. The case group included patients with chronic kidney disease (glomerular filtration rate lower than 60 ml/min/1.73m2, CKD-EPI formula); the control group included patients who did not suffer from chronic kidney disease. Preeclampsia diagnosis was established according to medical history. The statistical analysis comprised the chi-squared test (X2), odds ratio, logistic regression and event occurrence probability. Results: Among the chronic kidney disease patients, 80% reported a history of preeclampsia; 35% of subjects who did not suffer from chronic kidney disease also had a similar history (p=0.00). The time of evolution of preeclampsia and the diagnosis of chronic kidney disease was 7.5 years (95% CI: 7.10-7.89). The model which best explains chronic kidney disease includes preeclampsia and patient’s age (p=0.000), y=-3.444 + 1.794 (history of preeclampsia) + 0.082 (patient’s age). If the patient is 35 years old and has a history of preeclampsia, the probability of chronic kidney disease is 0.7721. Conclusion: Preeclampsia is a factor associated with chronic kidney disease.https://www.revistarenal.org.ar/index.php/rndt/article/view/463enfermedad renal crónicapreeclampsiaembarazofactores asociados
spellingShingle Enrique Villarreal Ríos
Paulina Itzel López Bejarano
Liliana Galicia Rodríguez
Emma Rosa Vargas Daza
Lidia Martínez González
Ariosto Lugo Rodríguez
Association between preeclampsia and chronic kidney disease
Revista de Nefrología, Diálisis y Trasplante
enfermedad renal crónica
preeclampsia
embarazo
factores asociados
title Association between preeclampsia and chronic kidney disease
title_full Association between preeclampsia and chronic kidney disease
title_fullStr Association between preeclampsia and chronic kidney disease
title_full_unstemmed Association between preeclampsia and chronic kidney disease
title_short Association between preeclampsia and chronic kidney disease
title_sort association between preeclampsia and chronic kidney disease
topic enfermedad renal crónica
preeclampsia
embarazo
factores asociados
url https://www.revistarenal.org.ar/index.php/rndt/article/view/463
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