Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells

Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells

Summary: Tumor vessel co-option, a process in which cancer cells “hijack” pre-existing blood vessels to grow and invade healthy tissue, is poorly understood but is a proposed resistance mechanism against anti-angiogenic therapy (AAT). Here, we describe protocols for establishing murine renal (RENCA)...

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Bibliographic Details
Main Authors: Anne Cuypers, Laure-Anne Teuwen, Victoria L. Bridgeman, Laura P.M.H. de Rooij, Guy Eelen, Mieke Dewerchin, Anna Rita Cantelmo, Joanna Kalucka, Ann Bouché, Stefan Vinckier, An Carton, Ann Manderveld, Peter B. Vermeulen, Andrew R. Reynolds, Peter Carmeliet
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:STAR Protocols
Subjects:
Antibody
Cancer
Cell isolation
Model organisms
Single cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166722005718

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