Pharmacophore-Based Discovery of Viral RNA Conformational Modulators

Pharmacophore-Based Discovery of Viral RNA Conformational Modulators

New RNA-binding small-molecule scaffolds are needed to unleash the pharmacological potential of RNA targets. Here we have applied a pharmacophore-based virtual screening approach, seldom used in the RNA recognition field, to identify novel conformational inhibitors of the hepatitis C virus internal...

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Bibliographic Details
Main Authors:	María Martín-Villamil, Isaías Sanmartín, Ángela Moreno, José Gallego
Format:	Article
Language:	English
Published:	MDPI AG 2022-06-01
Series:	Pharmaceuticals
Subjects:	bulge drug hepatitis C virus IRES junction pharmacophore
Online Access:	https://www.mdpi.com/1424-8247/15/6/748

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