TMO: time and memory optimized algorithm applicable for more accurate alignment of trinucleotide repeat disorders associated genes
In this study, time and memory optimized (TMO) algorithm is presented. Compared with Smith–Waterman's algorithm, TMO is applicable for a more accurate detection of continuous insertion/deletions (indels) in genes’ fragments, associated with disorders caused by over-repetition of a certain codon...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2016-03-01
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| Series: | Biotechnology & Biotechnological Equipment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/13102818.2015.1114428 |