Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications

John Panzone, Timothy Byler, Gennady Bratslavsky, Hanan Goldberg Urology Department, SUNY Upstate Medical University, Syracuse, NY, USACorrespondence: Hanan Goldberg, Urology Department, SUNY Upstate Medical University, Syracuse, NY, USA, Tel +1-315-271-4173, Email gohanan@gmail.comAbstract: Transre...

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Main Authors: Panzone J, Byler T, Bratslavsky G, Goldberg H
Format: Article
Language:English
Published: Dove Medical Press 2022-03-01
Series:Cancer Management and Research
Subjects:
Online Access:https://www.dovepress.com/transrectal-ultrasound-in-prostate-cancer-current-utilization-integrat-peer-reviewed-fulltext-article-CMAR
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author Panzone J
Byler T
Bratslavsky G
Goldberg H
author_facet Panzone J
Byler T
Bratslavsky G
Goldberg H
author_sort Panzone J
collection DOAJ
description John Panzone, Timothy Byler, Gennady Bratslavsky, Hanan Goldberg Urology Department, SUNY Upstate Medical University, Syracuse, NY, USACorrespondence: Hanan Goldberg, Urology Department, SUNY Upstate Medical University, Syracuse, NY, USA, Tel +1-315-271-4173, Email gohanan@gmail.comAbstract: Transrectal ultrasound (TRUS) has been an invaluable tool in the assessment of prostate size, anatomy and aiding in prostate cancer (PCa) diagnosis for decades. Emerging techniques warrant an investigation into the efficacy of TRUS, how it compares to new techniques, and options to increase the accuracy of prostate cancer diagnosis. Currently, TRUS is used to guide both transrectal and transperineal biopsy approaches with similar cancer detection rates, but lower rates of infection have been reported with the transperineal approach, while lower rates of urinary retention are often reported with the transrectal approach. Multiparametric MRI has substantial benefits for prostate cancer diagnosis and triage such as lesion location, grading, and can be combined with TRUS to perform fusion biopsies targeting specific lesions. Micro-ultrasound generates higher resolution images that traditional ultrasound and has been shown effective at diagnosing PCa, giving it the potential to become a future standard of care. Finally, high-intensity focused ultrasound focal therapy administered via TRUS has been shown to offer safe and effective short-term oncological control for localized disease with low morbidity, and the precise nature makes it a viable option for salvage and repeat therapy.Keywords: transrectal ultrasound, prostate cancer, transperineal biopsy
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spelling doaj.art-faa6bbca10084e959cdc8074bd39649c2022-12-21T23:32:41ZengDove Medical PressCancer Management and Research1179-13222022-03-01Volume 141209122873865Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging ApplicationsPanzone JByler TBratslavsky GGoldberg HJohn Panzone, Timothy Byler, Gennady Bratslavsky, Hanan Goldberg Urology Department, SUNY Upstate Medical University, Syracuse, NY, USACorrespondence: Hanan Goldberg, Urology Department, SUNY Upstate Medical University, Syracuse, NY, USA, Tel +1-315-271-4173, Email gohanan@gmail.comAbstract: Transrectal ultrasound (TRUS) has been an invaluable tool in the assessment of prostate size, anatomy and aiding in prostate cancer (PCa) diagnosis for decades. Emerging techniques warrant an investigation into the efficacy of TRUS, how it compares to new techniques, and options to increase the accuracy of prostate cancer diagnosis. Currently, TRUS is used to guide both transrectal and transperineal biopsy approaches with similar cancer detection rates, but lower rates of infection have been reported with the transperineal approach, while lower rates of urinary retention are often reported with the transrectal approach. Multiparametric MRI has substantial benefits for prostate cancer diagnosis and triage such as lesion location, grading, and can be combined with TRUS to perform fusion biopsies targeting specific lesions. Micro-ultrasound generates higher resolution images that traditional ultrasound and has been shown effective at diagnosing PCa, giving it the potential to become a future standard of care. Finally, high-intensity focused ultrasound focal therapy administered via TRUS has been shown to offer safe and effective short-term oncological control for localized disease with low morbidity, and the precise nature makes it a viable option for salvage and repeat therapy.Keywords: transrectal ultrasound, prostate cancer, transperineal biopsyhttps://www.dovepress.com/transrectal-ultrasound-in-prostate-cancer-current-utilization-integrat-peer-reviewed-fulltext-article-CMARtransrectal ultrasoundprostate cancertransperineal biopsy
spellingShingle Panzone J
Byler T
Bratslavsky G
Goldberg H
Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
Cancer Management and Research
transrectal ultrasound
prostate cancer
transperineal biopsy
title Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
title_full Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
title_fullStr Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
title_full_unstemmed Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
title_short Transrectal Ultrasound in Prostate Cancer: Current Utilization, Integration with mpMRI, HIFU and Other Emerging Applications
title_sort transrectal ultrasound in prostate cancer current utilization integration with mpmri hifu and other emerging applications
topic transrectal ultrasound
prostate cancer
transperineal biopsy
url https://www.dovepress.com/transrectal-ultrasound-in-prostate-cancer-current-utilization-integrat-peer-reviewed-fulltext-article-CMAR
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