Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation

Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation

The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. Using a fluorescence-based assay to study local com...

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Bibliographic Details
Main Authors: Tom Kruitwagen, Annina Denoth-Lippuner, Bryan J Wilkins, Heinz Neumann, Yves Barral
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
mitosis
chromosome condensation
chromosome segregation
Online Access:https://elifesciences.org/articles/10396

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