Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. Using a fluorescence-based assay to study local com...
Main Authors: | Tom Kruitwagen, Annina Denoth-Lippuner, Bryan J Wilkins, Heinz Neumann, Yves Barral |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2015-11-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/10396 |
Similar Items
-
Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation
by: Jonay Garcia-Luis, et al.
Published: (2022-10-01) -
Fission yeast neddylation ligase Dcn1 facilitates cohesin cleavage and chromosome segregation at anaphase
by: Lan Lin, et al.
Published: (2017-06-01) -
Visualization of chromosome condensation in plants with large chromosomes
by: Maria A. Kuznetsova, et al.
Published: (2017-09-01) -
They Might Cut It—Lysosomes and Autophagy in Mitotic Progression
by: Saara Hämälistö, et al.
Published: (2021-08-01) -
The TFIIH complex is required to establish and maintain mitotic chromosome structure
by: Julian Haase, et al.
Published: (2022-03-01)