Heat-killed Prevotella intermedia promotes the progression of oral squamous cell carcinoma by inhibiting the expression of tumor suppressors and affecting the tumor microenvironment

Heat-killed Prevotella intermedia promotes the progression of oral squamous cell carcinoma by inhibiting the expression of tumor suppressors and affecting the tumor microenvironment

Abstract Background Oral microbial dysbiosis contributes to the development of oral squamous cell carcinoma (OSCC). Our previous study showed that Prevotella intermedia (P. intermedia) were enriched in the oral mucosal surface, plaque, and saliva of patients with OSCC. Intratumoral microbiome could...

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Bibliographic Details
Main Authors: Yifan Zhou, Yao Qin, Jingjing Ma, Zhiyuan Li, Weiwei Heng, Lei Zhang, Hong Liu, Ruowei Li, Miaomiao Zhang, Qiao Peng, Pei Ye, Ning Duan, Ting Liu, Wenmei Wang, Xiang Wang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Experimental Hematology & Oncology
Subjects:
Oral squamous cell carcinoma
Prevotella intermedia
IL-17 signal pathway
GABAergic system
Tumor suppressor genes
Online Access:https://doi.org/10.1186/s40164-024-00500-y

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