Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study
Background: The impacts of smoking on the intestinal microbiome piece and arranged assortment have been appeared in different arranged controlled and observational clinical trials in individuals. Synbiotics are utilized not fair for the progressed survival of beneficial microorganisms included to foo...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2020-01-01
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| Series: | Asian Journal of Medical Sciences |
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| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/26495 |
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| author | Parama Pratummas Vachrintr Sirisapsombat Phuttharaksa Phucharoen Thamthiwat Nararatwanchai Chaiyavat Chaiyasut Sasithorn Sirilun Phakkharawat Sittiprapaporn |
| author_facet | Parama Pratummas Vachrintr Sirisapsombat Phuttharaksa Phucharoen Thamthiwat Nararatwanchai Chaiyavat Chaiyasut Sasithorn Sirilun Phakkharawat Sittiprapaporn |
| author_sort | Parama Pratummas |
| collection | DOAJ |
| description | Background: The impacts of smoking on the intestinal microbiome piece and arranged assortment have been appeared in different arranged controlled and observational clinical trials in individuals. Synbiotics are utilized not fair for the progressed survival of beneficial microorganisms included to food, however in expansion for the prompting of the duplication of specific nearby bacterial strains display within the gastrointestinal tract.
Aims and Objective: This research proposes the impact of synbiotic supplement on gut-brain axis in Thai smokers in the realm of gut-related biochemical parameters and cognition.
Materials and Methods: We directed a single gathering, pre-and post-test study; 20 patients lived in Mahasarakham, Fagerstrom Test for Nicotine Dependence at 4 or above, and no history of cerebrovascular diseases, brain and abdominal surgery, and not taking hormones or medications impacted brainwaves or utilizing antibiotics inside about fourteen days prior. Subjects were allocated to synbiotic supplement containing 3 kinds of prebiotics and 7 types of probiotics prior to sleep every day for about two months.
Results:Results were estimated in gut-related biochemical parameters change and alternation in cognition. The present outcomes have indicated essentially decline in the scores of Fagerstrom Test for Nicotine Dependence and also the scores of craving for smoke after intervention. In additions, lipopolysaccharide (LPS) in plasma significantly decreased after the intervention.
Conclusion: Further researches are obligatory to lead in finding a propensity to improve in gut-related biochemical parameter and cognition after admission of synbiotic supplement. |
| first_indexed | 2024-12-18T19:16:23Z |
| format | Article |
| id | doaj.art-faba7e42db5e4a59ab245a1b38b60d82 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-12-18T19:16:23Z |
| publishDate | 2020-01-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-faba7e42db5e4a59ab245a1b38b60d822022-12-21T20:56:08ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762020-01-011111621https://doi.org/10.3126/ajms.v11i1.26495Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary studyParama Pratummas0Vachrintr Sirisapsombat 1Phuttharaksa Phucharoen2Thamthiwat Nararatwanchai3Chaiyavat Chaiyasut4Sasithorn Sirilun 5Phakkharawat Sittiprapaporn6Doctoral Student, Brain Science and Engineering Innovation Research Group, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand, and Department of Anti-Aging Medicine, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand https://orcid.org/0000-0002-1472-3803Doctoral Student, Brain Science and Engineering Innovation Research Group, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand, and Department of Anti-Aging Medicine, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand https://orcid.org/0000-0003-3575-6759Doctoral Student, Brain Science and Engineering Innovation Research Group, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand, and Department of Anti-Aging Medicine, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand https://orcid.org/0000-0002-4438-9172Professor, Department of Anti-Aging Medicine, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand https://orcid.org/0000-0002-4189-8115Assistant Professor and Head, Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy,Chiang Mai University, Chiang Mai, Thailand https://orcid.org/0000-0002-1633-2419Assistant Professor, Innovation Center for Holistic Health, Nutraceuticals and Cosmeceuticals, Faculty of Pharmacy,Chiang Mai University, Chiang Mai, Thailand https://orcid.org/0000-0002-1508-2358Assistant Professor and Head, Brain Science and Engineering Innovation Research Group, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand, and Department of Anti-Aging Science, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand https://orcid.org/0000-0002-4103-9396Background: The impacts of smoking on the intestinal microbiome piece and arranged assortment have been appeared in different arranged controlled and observational clinical trials in individuals. Synbiotics are utilized not fair for the progressed survival of beneficial microorganisms included to food, however in expansion for the prompting of the duplication of specific nearby bacterial strains display within the gastrointestinal tract. Aims and Objective: This research proposes the impact of synbiotic supplement on gut-brain axis in Thai smokers in the realm of gut-related biochemical parameters and cognition. Materials and Methods: We directed a single gathering, pre-and post-test study; 20 patients lived in Mahasarakham, Fagerstrom Test for Nicotine Dependence at 4 or above, and no history of cerebrovascular diseases, brain and abdominal surgery, and not taking hormones or medications impacted brainwaves or utilizing antibiotics inside about fourteen days prior. Subjects were allocated to synbiotic supplement containing 3 kinds of prebiotics and 7 types of probiotics prior to sleep every day for about two months. Results:Results were estimated in gut-related biochemical parameters change and alternation in cognition. The present outcomes have indicated essentially decline in the scores of Fagerstrom Test for Nicotine Dependence and also the scores of craving for smoke after intervention. In additions, lipopolysaccharide (LPS) in plasma significantly decreased after the intervention. Conclusion: Further researches are obligatory to lead in finding a propensity to improve in gut-related biochemical parameter and cognition after admission of synbiotic supplement.https://www.nepjol.info/index.php/AJMS/article/view/26495synbioticsgut microbiotagut-brain axiscigarette smokercognition |
| spellingShingle | Parama Pratummas Vachrintr Sirisapsombat Phuttharaksa Phucharoen Thamthiwat Nararatwanchai Chaiyavat Chaiyasut Sasithorn Sirilun Phakkharawat Sittiprapaporn Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study Asian Journal of Medical Sciences synbiotics gut microbiota gut-brain axis cigarette smoker cognition |
| title | Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study |
| title_full | Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study |
| title_fullStr | Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study |
| title_full_unstemmed | Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study |
| title_short | Effects of synbiotic supplement on LPS level in Thai smokers: A preliminary study |
| title_sort | effects of synbiotic supplement on lps level in thai smokers a preliminary study |
| topic | synbiotics gut microbiota gut-brain axis cigarette smoker cognition |
| url | https://www.nepjol.info/index.php/AJMS/article/view/26495 |
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