Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis
The aim of this review is to investigate the association between metabolic syndrome (MetS) and cognitive decline in distinct cognitive domains, and to perform a complementary study description through the bibliometric analysis. PubMed and Scopus databases were searched from inception to 15 December...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-11-01
|
| Series: | Frontiers in Psychology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.981379/full |
| _version_ | 1798023221266612224 |
|---|---|
| author | Myrto Koutsonida Georgios Markozannes Emmanouil Bouras Emmanouil Bouras Eleni Aretouli Eleni Aretouli Konstantinos K. Tsilidis Konstantinos K. Tsilidis |
| author_facet | Myrto Koutsonida Georgios Markozannes Emmanouil Bouras Emmanouil Bouras Eleni Aretouli Eleni Aretouli Konstantinos K. Tsilidis Konstantinos K. Tsilidis |
| author_sort | Myrto Koutsonida |
| collection | DOAJ |
| description | The aim of this review is to investigate the association between metabolic syndrome (MetS) and cognitive decline in distinct cognitive domains, and to perform a complementary study description through the bibliometric analysis. PubMed and Scopus databases were searched from inception to 15 December 2021 to identify longitudinal studies that examined the association of MetS with incident decline, in order to prevent reverse causality. The Preferred Reporting Items for Systematic Review and Meta-Analysis checklist was used to conduct the present systematic review. Thirty studies were included and results were analyzed across the cognitive domains of global cognition, memory, executive functions, attention, visuoconstructive abilities, and language. The majority of the studies reviewed did not report statistically significant results for most cognitive domains investigated, and decline in specific cognitive domains was not consistently associated with the presence of MetS. Meta-analyses were not conducted due to the high degree of between-study heterogeneity regarding the MetS definitions, the cognitive domains examined, the specific tests used for each cognitive domain and the different measures of association used. Bibliometric analysis revealed that most studies are conducted by research teams from USA and China, and that cognitive tasks that reflect real-life abilities are rarely examined. Future studies should employ larger sample sizes, longer follow-up periods, a global consensus for MetS definition and standardized tests of the above mentioned cognitive domains as well as problem-solving tasks with high sensitivity and specificity to clarify the impact of MetS on cognition and its underlying mechanisms. |
| first_indexed | 2024-04-11T17:42:51Z |
| format | Article |
| id | doaj.art-faba96a5f1314325b64899ee35231317 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-04-11T17:42:51Z |
| publishDate | 2022-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-faba96a5f1314325b64899ee352313172022-12-22T04:11:27ZengFrontiers Media S.A.Frontiers in Psychology1664-10782022-11-011310.3389/fpsyg.2022.981379981379Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysisMyrto Koutsonida0Georgios Markozannes1Emmanouil Bouras2Emmanouil Bouras3Eleni Aretouli4Eleni Aretouli5Konstantinos K. Tsilidis6Konstantinos K. Tsilidis7Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, GreeceDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, GreeceDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, GreeceLaboratory of Hygiene, Social & Preventive Medicine and Medical Statistics, Department of Medicine, School of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GreeceDepartment of Psychology, School of Social Sciences, University of Ioannina, Ioannina, GreeceLaboratory of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, GreeceDepartment of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, GreeceDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United KingdomThe aim of this review is to investigate the association between metabolic syndrome (MetS) and cognitive decline in distinct cognitive domains, and to perform a complementary study description through the bibliometric analysis. PubMed and Scopus databases were searched from inception to 15 December 2021 to identify longitudinal studies that examined the association of MetS with incident decline, in order to prevent reverse causality. The Preferred Reporting Items for Systematic Review and Meta-Analysis checklist was used to conduct the present systematic review. Thirty studies were included and results were analyzed across the cognitive domains of global cognition, memory, executive functions, attention, visuoconstructive abilities, and language. The majority of the studies reviewed did not report statistically significant results for most cognitive domains investigated, and decline in specific cognitive domains was not consistently associated with the presence of MetS. Meta-analyses were not conducted due to the high degree of between-study heterogeneity regarding the MetS definitions, the cognitive domains examined, the specific tests used for each cognitive domain and the different measures of association used. Bibliometric analysis revealed that most studies are conducted by research teams from USA and China, and that cognitive tasks that reflect real-life abilities are rarely examined. Future studies should employ larger sample sizes, longer follow-up periods, a global consensus for MetS definition and standardized tests of the above mentioned cognitive domains as well as problem-solving tasks with high sensitivity and specificity to clarify the impact of MetS on cognition and its underlying mechanisms.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.981379/fullmetabolic syndromecognitive domainssystematic reviewlongitudinal designbibliometric analysis |
| spellingShingle | Myrto Koutsonida Georgios Markozannes Emmanouil Bouras Emmanouil Bouras Eleni Aretouli Eleni Aretouli Konstantinos K. Tsilidis Konstantinos K. Tsilidis Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis Frontiers in Psychology metabolic syndrome cognitive domains systematic review longitudinal design bibliometric analysis |
| title | Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis |
| title_full | Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis |
| title_fullStr | Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis |
| title_full_unstemmed | Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis |
| title_short | Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis |
| title_sort | metabolic syndrome and cognition a systematic review across cognitive domains and a bibliometric analysis |
| topic | metabolic syndrome cognitive domains systematic review longitudinal design bibliometric analysis |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.981379/full |
| work_keys_str_mv | AT myrtokoutsonida metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT georgiosmarkozannes metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT emmanouilbouras metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT emmanouilbouras metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT eleniaretouli metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT eleniaretouli metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT konstantinosktsilidis metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis AT konstantinosktsilidis metabolicsyndromeandcognitionasystematicreviewacrosscognitivedomainsandabibliometricanalysis |