HPLC-MS/MS Oxylipin Analysis of Plasma from Amyotrophic Lateral Sclerosis Patients

HPLC-MS/MS Oxylipin Analysis of Plasma from Amyotrophic Lateral Sclerosis Patients

Oxylipins play a critical role in regulating the onset and resolution phase of inflammation. Despite inflammation is a pathological hallmark in amyotrophic lateral sclerosis (ALS), the plasma oxylipin profile of ALS patients has not been assessed yet. Herein, we develop an oxylipin profile-targeted...

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Bibliographic Details
Main Authors: Mauricio Mastrogiovanni, Andrés Trostchansky, Hugo Naya, Raúl Dominguez, Carla Marco, Mònica Povedano, Rubèn López-Vales, Homero Rubbo
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomedicines
Subjects:
amyotrophic lateral sclerosis
lipidomics
oxylipin
specialized pro-resolving mediators
mass spectrometry
Online Access:https://www.mdpi.com/2227-9059/10/3/674

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