Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident
Diffused Axonal Injury (DAI) is a form of mild Traumatic Brain Injury (TBI) that occurs when there are rapid acceleration and deceleration of the head caused by road traffic accidents. It results in the accumulation of Amyloid Precursor Protein (APP) and increased calcium that causes damage to the...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2020-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/13972/44690_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdf |
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| author | Mohammed Eliyas Abishek Umashankar G Amritha |
| author_facet | Mohammed Eliyas Abishek Umashankar G Amritha |
| author_sort | Mohammed Eliyas |
| collection | DOAJ |
| description | Diffused Axonal Injury (DAI) is a form of mild Traumatic Brain Injury (TBI) that occurs when there are rapid acceleration and
deceleration of the head caused by road traffic accidents. It results in the accumulation of Amyloid Precursor Protein (APP) and
increased calcium that causes damage to the axonal cytoskeleton and ion channels, hence resulting in degeneration. This report is
of 35 year old male patient with DAI secondary to road traffic accident, where a complete audiological test battery was done. Upon
multiple Computed Tomography (CT) investigations, the third CT findings revealed a hypodensity at the level of upper brainstem.
Upon audiological evaluation, the patient had a moderate sensorineural hearing loss in the left ear and a mild sensorineural hearing
loss in the right ear. The speech discrimination scores were poor in both the ears, thus suggesting a presence of a Retrocochlear
involvement. On administering Auditory Brainstem Response (ABR), no V peak could be visualised in both ears, thus indicating
a lesion at the upper brainstem which correlated with CT findings and on administering various other test batteries, findings
revealed a presence of retrocochlear involvement. This study highlights the importance of carrying out both Electrophysiological
and Radiological test procedures in diagnosing DAI. |
| first_indexed | 2024-12-17T22:46:09Z |
| format | Article |
| id | doaj.art-fac5b16a87534494bc229ce5a8cb529e |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-17T22:46:09Z |
| publishDate | 2020-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-fac5b16a87534494bc229ce5a8cb529e2022-12-21T21:29:47ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-09-01149MD01MD0310.7860/JCDR/2020/44690.13972Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic AccidentMohammed Eliyas0Abishek Umashankar1 G Amritha2Clinical Audiologist, Department of Audiology, MERF Institute of Speech and Hearing (p) Ltd., Chennai, Tamil Nadu, India.Postgraduate, Department of Audiology, MERF Institute of Speech and Hearing (p) Ltd., Chennai, Tamil Nadu, India.Audiologist, Department of Audiology, MERF Institute of Speech and Hearing (p) Ltd., Chennai, Tamil Nadu, India.Diffused Axonal Injury (DAI) is a form of mild Traumatic Brain Injury (TBI) that occurs when there are rapid acceleration and deceleration of the head caused by road traffic accidents. It results in the accumulation of Amyloid Precursor Protein (APP) and increased calcium that causes damage to the axonal cytoskeleton and ion channels, hence resulting in degeneration. This report is of 35 year old male patient with DAI secondary to road traffic accident, where a complete audiological test battery was done. Upon multiple Computed Tomography (CT) investigations, the third CT findings revealed a hypodensity at the level of upper brainstem. Upon audiological evaluation, the patient had a moderate sensorineural hearing loss in the left ear and a mild sensorineural hearing loss in the right ear. The speech discrimination scores were poor in both the ears, thus suggesting a presence of a Retrocochlear involvement. On administering Auditory Brainstem Response (ABR), no V peak could be visualised in both ears, thus indicating a lesion at the upper brainstem which correlated with CT findings and on administering various other test batteries, findings revealed a presence of retrocochlear involvement. This study highlights the importance of carrying out both Electrophysiological and Radiological test procedures in diagnosing DAI.https://jcdr.net/articles/PDF/13972/44690_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdfamyloid precursor proteinauditory evoked potentialbrainstemradiologytraumatic brain injury |
| spellingShingle | Mohammed Eliyas Abishek Umashankar G Amritha Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident Journal of Clinical and Diagnostic Research amyloid precursor protein auditory evoked potential brainstem radiology traumatic brain injury |
| title | Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident |
| title_full | Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident |
| title_fullStr | Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident |
| title_full_unstemmed | Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident |
| title_short | Audiological Findings in Diffused Axonal Injury Secondary to Road Traffic Accident |
| title_sort | audiological findings in diffused axonal injury secondary to road traffic accident |
| topic | amyloid precursor protein auditory evoked potential brainstem radiology traumatic brain injury |
| url | https://jcdr.net/articles/PDF/13972/44690_CE[Ra1]_F(SHU)_PF1(AG_KM)_PFA(KM)_PB(AG_KM)_PN(SL).pdf |
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