Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?

As the advanced form of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) will significantly increase the risks of liver fibrosis, cirrhosis, and HCC. However, there is no non-invasive method to distinguish NASH from NAFLD so far. Additionally, liver biopsy remains the go...

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Main Authors: Lei Zhang, Yilei Mao
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/11/1/117
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author Lei Zhang
Yilei Mao
author_facet Lei Zhang
Yilei Mao
author_sort Lei Zhang
collection DOAJ
description As the advanced form of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) will significantly increase the risks of liver fibrosis, cirrhosis, and HCC. However, there is no non-invasive method to distinguish NASH from NAFLD so far. Additionally, liver biopsy remains the gold standard to diagnose NASH, which is not appropriate for routine screening. Recently, artificial intelligence (AI) is under rapid development in many aspects of medicine. Additionally, the application of AI in clinical information may have the potential to diagnose NASH non-invasively. This review summarizes the latest research using AI, specifically machine learning, to facilitate the diagnosis, prognosis, and monitoring of NAFLD. Additionally, according to our prior results, this work proposes future development in this area.
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spelling doaj.art-fac82126ce1f46918600d6f29f5771e12023-11-16T15:25:48ZengMDPI AGHealthcare2227-90322022-12-0111111710.3390/healthcare11010117Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?Lei Zhang0Yilei Mao1Department of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaDepartment of Liver Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, ChinaAs the advanced form of nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH) will significantly increase the risks of liver fibrosis, cirrhosis, and HCC. However, there is no non-invasive method to distinguish NASH from NAFLD so far. Additionally, liver biopsy remains the gold standard to diagnose NASH, which is not appropriate for routine screening. Recently, artificial intelligence (AI) is under rapid development in many aspects of medicine. Additionally, the application of AI in clinical information may have the potential to diagnose NASH non-invasively. This review summarizes the latest research using AI, specifically machine learning, to facilitate the diagnosis, prognosis, and monitoring of NAFLD. Additionally, according to our prior results, this work proposes future development in this area.https://www.mdpi.com/2227-9032/11/1/117artificial intelligencenonalcoholic fatty liver diseasenonalcoholic steatohepatitisdiagnosis
spellingShingle Lei Zhang
Yilei Mao
Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
Healthcare
artificial intelligence
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
diagnosis
title Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
title_full Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
title_fullStr Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
title_full_unstemmed Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
title_short Artificial Intelligence in NAFLD: Will Liver Biopsy Still Be Necessary in the Future?
title_sort artificial intelligence in nafld will liver biopsy still be necessary in the future
topic artificial intelligence
nonalcoholic fatty liver disease
nonalcoholic steatohepatitis
diagnosis
url https://www.mdpi.com/2227-9032/11/1/117
work_keys_str_mv AT leizhang artificialintelligenceinnafldwillliverbiopsystillbenecessaryinthefuture
AT yileimao artificialintelligenceinnafldwillliverbiopsystillbenecessaryinthefuture