Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy
BackgroundThis analysis addresses the uncertainty surrounding the efficacy of glue mesh fixation (GMF) compared with tack mesh fixation (TMF) in laparoscopic herniorrhaphy. Our meta-analysis incorporates recently conducted randomized controlled trials (RCTs) to enhance the reference for assessing th...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-02-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1321325/full |
| _version_ | 1797319523866509312 |
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| author | Sandesh Raja Adarsh Raja Ziyan Ansari Sara Eman Simran Bajaj Muhammad Ahmed Uday Kumar Yawar Hussain Shah Sachin Jawahar Faisal Aftab Deepak Rajani Satesh Kumar Mahima Khatri |
| author_facet | Sandesh Raja Adarsh Raja Ziyan Ansari Sara Eman Simran Bajaj Muhammad Ahmed Uday Kumar Yawar Hussain Shah Sachin Jawahar Faisal Aftab Deepak Rajani Satesh Kumar Mahima Khatri |
| author_sort | Sandesh Raja |
| collection | DOAJ |
| description | BackgroundThis analysis addresses the uncertainty surrounding the efficacy of glue mesh fixation (GMF) compared with tack mesh fixation (TMF) in laparoscopic herniorrhaphy. Our meta-analysis incorporates recently conducted randomized controlled trials (RCTs) to enhance the reference for assessing the efficacy and safety of GMF.MethodsPubMed Central, Google Scholar, Science Direct, and Cochrane Library were extensively reviewed for articles in the English language performed from inception to May 2023 using the keywords “Glue mesh repair,” “Tack mesh repair,” “Inguinal Hernia,” “Herniorrhaphy,” “Laparoscopic,” “Mesh Fixation,” and “Randomized controlled trials.”ResultsIn this meta-analysis, we incorporated a total of 20 randomized controlled trials, evaluating each article individually using quality ratings. Compared with TMF, GMF demonstrated a significant reduction in the incidence of chronic pain [RR: 0.40, (0.23, 0.68)] and pain scores on postoperative day 1 [MD: −1.07, (−1.90, −0.25)]. We also used funnel plots and Egger's regression to test for publication bias.ConclusionIn summary, this meta-analysis establishes the significance of GMF in reducing chronic pain and postoperative day 1 pain compared with TMF. However, no statistically significant difference was noted between the GMF and TMF groups concerning hematoma, seroma, operation time, recurrence rate, and total complications. Nonetheless, given the small number of cases in this study, the findings must be validated in the future by multicenter, large-sample, high-quality RCTs. |
| first_indexed | 2024-03-08T04:08:07Z |
| format | Article |
| id | doaj.art-faca3e2a70bd47fb87d1dc3c67bc7856 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-08T04:08:07Z |
| publishDate | 2024-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-faca3e2a70bd47fb87d1dc3c67bc78562024-02-09T04:43:04ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2024-02-011110.3389/fsurg.2024.13213251321325Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphySandesh Raja0Adarsh Raja1Ziyan Ansari2Sara Eman3Simran Bajaj4Muhammad Ahmed5Uday Kumar6Yawar Hussain Shah7Sachin Jawahar8Faisal Aftab9Deepak Rajani10Satesh Kumar11Mahima Khatri12Department of Surgery, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanDepartment of Surgery, Foundation University Medical College, Islamabad, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Liaquat College of Medicine and Dentistry, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Shaheed Mohtarma Benazir Bhutto Medical College Lyari, Karachi, PakistanDepartment of Surgery, Dow Medical College, Dow University of Health Sciences, Karachi, PakistanBackgroundThis analysis addresses the uncertainty surrounding the efficacy of glue mesh fixation (GMF) compared with tack mesh fixation (TMF) in laparoscopic herniorrhaphy. Our meta-analysis incorporates recently conducted randomized controlled trials (RCTs) to enhance the reference for assessing the efficacy and safety of GMF.MethodsPubMed Central, Google Scholar, Science Direct, and Cochrane Library were extensively reviewed for articles in the English language performed from inception to May 2023 using the keywords “Glue mesh repair,” “Tack mesh repair,” “Inguinal Hernia,” “Herniorrhaphy,” “Laparoscopic,” “Mesh Fixation,” and “Randomized controlled trials.”ResultsIn this meta-analysis, we incorporated a total of 20 randomized controlled trials, evaluating each article individually using quality ratings. Compared with TMF, GMF demonstrated a significant reduction in the incidence of chronic pain [RR: 0.40, (0.23, 0.68)] and pain scores on postoperative day 1 [MD: −1.07, (−1.90, −0.25)]. We also used funnel plots and Egger's regression to test for publication bias.ConclusionIn summary, this meta-analysis establishes the significance of GMF in reducing chronic pain and postoperative day 1 pain compared with TMF. However, no statistically significant difference was noted between the GMF and TMF groups concerning hematoma, seroma, operation time, recurrence rate, and total complications. Nonetheless, given the small number of cases in this study, the findings must be validated in the future by multicenter, large-sample, high-quality RCTs.https://www.frontiersin.org/articles/10.3389/fsurg.2024.1321325/fullinguinal hernialaparoscopic herniorrhaphyglue mesh fixationtack mesh fixationhernia |
| spellingShingle | Sandesh Raja Adarsh Raja Ziyan Ansari Sara Eman Simran Bajaj Muhammad Ahmed Uday Kumar Yawar Hussain Shah Sachin Jawahar Faisal Aftab Deepak Rajani Satesh Kumar Mahima Khatri Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy Frontiers in Surgery inguinal hernia laparoscopic herniorrhaphy glue mesh fixation tack mesh fixation hernia |
| title | Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| title_full | Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| title_fullStr | Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| title_full_unstemmed | Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| title_short | Safety and efficacy revisited: a systematic review and meta-analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| title_sort | safety and efficacy revisited a systematic review and meta analysis of glue versus tack mesh fixation in laparoscopic inguinal herniorrhaphy |
| topic | inguinal hernia laparoscopic herniorrhaphy glue mesh fixation tack mesh fixation hernia |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2024.1321325/full |
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