Mucosal Immune Profiles Associated with Diarrheal Disease Severity in Shigella- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study

ABSTRACT Enteropathogenic Escherichia coli (EPEC) and Shigella are etiologic agents of diarrhea in children <5 years old living in resource-poor countries. Repeated bouts of infection lead to lifelong morbidity and even death. The goal of this study was to characterize local mucosal immune respon...

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Main Authors: Amanda D. Buskirk, Esther Ndungo, Avital A. Shimanovich, Diana Lam, William C. Blackwelder, Usman N. Ikumapayi, Bing Ma, Helen Powell, Martin Antonio, James P. Nataro, James B. Kaper, Marcela F. Pasetti
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.00538-22