Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i>
Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of seco...
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MDPI AG
2022-02-01
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| Online Access: | https://www.mdpi.com/2297-8739/9/2/41 |
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| author | Beatriz Sepúlveda Alberto Cornejo Daniela Bárcenas-Pérez José Cheel Carlos Areche |
| author_facet | Beatriz Sepúlveda Alberto Cornejo Daniela Bárcenas-Pérez José Cheel Carlos Areche |
| author_sort | Beatriz Sepúlveda |
| collection | DOAJ |
| description | Lichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of secondary metabolites from natural sources. Twenty-five compounds were detected from the Antarctic lichen <i>Cladonia metacorallifera</i> for the first time using UHPLC-PDA/ESI/Orbitrap/MS/MS. Compounds <b>5</b> and <b>7</b> are reported as new compounds, based on their MS/MS fragmentation routes, and considered as fumarprotocetraric acid derivatives. Besides, ten known phenolic identified as orsellinic acid, ethyl 4-carboxyorsellinate, psoromic acid isomer, succinprotocetraric acid, siphulellic acid, connorstictic acid, cryptostictic acid, lecanoric acid, lobaric acid and gyrophoric acid are noticed for the first time in the <i>Cladonia</i> genus. |
| first_indexed | 2024-03-09T21:05:44Z |
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| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-09T21:05:44Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
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| spelling | doaj.art-fad0e0a543fe42be96d12738d7d57ede2023-11-23T22:03:59ZengMDPI AGSeparations2297-87392022-02-01924110.3390/separations9020041Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i>Beatriz Sepúlveda0Alberto Cornejo1Daniela Bárcenas-Pérez2José Cheel3Carlos Areche4Departamento de Ciencias Químicas, Campus Viña del Mar, Universidad Andrés Bello, Quillota 980, Viña del Mar 2520000, ChileFacultad de Medicina, Escuela de Tecnología Médica, Universidad Andrés Bello, Sazié 2315, Primer Piso, Santiago 8370092, ChileLaboratory of Algal Biotechnology—Centre ALGATECH, Institute of Microbiology of the Czech Academy of Sciences, Opatovicky Mlyn, 37981 Trebon, Czech RepublicLaboratory of Algal Biotechnology—Centre ALGATECH, Institute of Microbiology of the Czech Academy of Sciences, Opatovicky Mlyn, 37981 Trebon, Czech RepublicDepartamento de Química, Facultad de Ciencias, Universidad de Chile, Santiago 8320000, ChileLichens are symbiotic organisms between algae and fungi, which are makers of secondary compounds named as lichen substances. Hyphenated techniques have significantly helped natural product chemistry, especially UHPLC/ESI/MS/MS in the identification, separation, and tentative characterization of secondary metabolites from natural sources. Twenty-five compounds were detected from the Antarctic lichen <i>Cladonia metacorallifera</i> for the first time using UHPLC-PDA/ESI/Orbitrap/MS/MS. Compounds <b>5</b> and <b>7</b> are reported as new compounds, based on their MS/MS fragmentation routes, and considered as fumarprotocetraric acid derivatives. Besides, ten known phenolic identified as orsellinic acid, ethyl 4-carboxyorsellinate, psoromic acid isomer, succinprotocetraric acid, siphulellic acid, connorstictic acid, cryptostictic acid, lecanoric acid, lobaric acid and gyrophoric acid are noticed for the first time in the <i>Cladonia</i> genus.https://www.mdpi.com/2297-8739/9/2/41Antarctica<i>Cladonia</i>depsidesdepsidonesFumarprotocetraric acidlichens |
| spellingShingle | Beatriz Sepúlveda Alberto Cornejo Daniela Bárcenas-Pérez José Cheel Carlos Areche Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> Separations Antarctica <i>Cladonia</i> depsides depsidones Fumarprotocetraric acid lichens |
| title | Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> |
| title_full | Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> |
| title_fullStr | Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> |
| title_full_unstemmed | Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> |
| title_short | Two New Fumarprotocetraric Acid Lactones Identified and Characterized by UHPLC-PDA/ESI/ORBITRAP/MS/MS from the Antarctic Lichen <i>Cladonia metacorallifera</i> |
| title_sort | two new fumarprotocetraric acid lactones identified and characterized by uhplc pda esi orbitrap ms ms from the antarctic lichen i cladonia metacorallifera i |
| topic | Antarctica <i>Cladonia</i> depsides depsidones Fumarprotocetraric acid lichens |
| url | https://www.mdpi.com/2297-8739/9/2/41 |
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