Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study
Background/Aim: Hypomagnesaemia has been shown to have a significant impact on both glycaemic control and diabetes complications in type 2 diabetes mellitus (T2DM) patients. This study aims to assess the prevalence of hypomagnesaemia in T2DM patients and find the association between serum magnesium...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2022;volume=26;issue=6;spage=575;epage=580;aulast=Hamarshih |
| _version_ | 1797775255129817088 |
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| author | Mohammad Hamarshih Suha Hamshari Zaher Nazzal Farha Snobar Rawa Mletat Ola Abu-Mazen Beesan Maraqa |
| author_facet | Mohammad Hamarshih Suha Hamshari Zaher Nazzal Farha Snobar Rawa Mletat Ola Abu-Mazen Beesan Maraqa |
| author_sort | Mohammad Hamarshih |
| collection | DOAJ |
| description | Background/Aim: Hypomagnesaemia has been shown to have a significant impact on both glycaemic control and diabetes complications in type 2 diabetes mellitus (T2DM) patients. This study aims to assess the prevalence of hypomagnesaemia in T2DM patients and find the association between serum magnesium levels and outcomes relevant to glycaemic control and diabetic complications in primary care unit. Methods: A cross-sectional study was conducted and included 373 patients (222 males and 151 females) from primary care unit. Serum magnesium levels were measured by the colorimetric endpoint method using the Cobas C501 system. Hypomagnesaemia was determined to be a serum magnesium level <1.6 mg/dL. In addition, the following data was also obtained: patients' characteristics, anthropometric measurements, smoking status, HbA1c, comorbidities and therapeutic management. Results: Patients' mean age was 56.2 ± 10.8 years, 24.6% were smokers, and most were overweight or obese. About 60% have a history of hypertension, and the majority have had diabetes for more than 10 years. Their mean HbA1c level was 8.5 ± 2%. The prevalence of hypomagnesaemia was 11% (95% CI: 8%–14.6%). It was found to be significantly higher among females (adjusted OR: 2.7, 95%CI: 1.2%–5.8%), patients with HbA1c ≥8% (adjusted OR: 2.4, 95%CI: 1.1%–5.5%) and patients with a history of diabetic retinopathy (adjusted OR: 2.7, 95%CI: 1.1%–7.1%). Conclusion: The study showed that hypomagnesaemia is more prevalent in females and is associated with diabetic retinopathy and poor glycaemic control. Having a sufficient magnesium level may be associated with better glycaemic control and a reduced occurrence of complications. |
| first_indexed | 2024-03-12T22:32:08Z |
| format | Article |
| id | doaj.art-fad49293c7bd4f1b8a465bd8fbfe1e25 |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-03-12T22:32:08Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-fad49293c7bd4f1b8a465bd8fbfe1e252023-07-21T14:56:04ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102022-01-0126657558010.4103/ijem.ijem_213_22Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional studyMohammad HamarshihSuha HamshariZaher NazzalFarha SnobarRawa MletatOla Abu-MazenBeesan MaraqaBackground/Aim: Hypomagnesaemia has been shown to have a significant impact on both glycaemic control and diabetes complications in type 2 diabetes mellitus (T2DM) patients. This study aims to assess the prevalence of hypomagnesaemia in T2DM patients and find the association between serum magnesium levels and outcomes relevant to glycaemic control and diabetic complications in primary care unit. Methods: A cross-sectional study was conducted and included 373 patients (222 males and 151 females) from primary care unit. Serum magnesium levels were measured by the colorimetric endpoint method using the Cobas C501 system. Hypomagnesaemia was determined to be a serum magnesium level <1.6 mg/dL. In addition, the following data was also obtained: patients' characteristics, anthropometric measurements, smoking status, HbA1c, comorbidities and therapeutic management. Results: Patients' mean age was 56.2 ± 10.8 years, 24.6% were smokers, and most were overweight or obese. About 60% have a history of hypertension, and the majority have had diabetes for more than 10 years. Their mean HbA1c level was 8.5 ± 2%. The prevalence of hypomagnesaemia was 11% (95% CI: 8%–14.6%). It was found to be significantly higher among females (adjusted OR: 2.7, 95%CI: 1.2%–5.8%), patients with HbA1c ≥8% (adjusted OR: 2.4, 95%CI: 1.1%–5.5%) and patients with a history of diabetic retinopathy (adjusted OR: 2.7, 95%CI: 1.1%–7.1%). Conclusion: The study showed that hypomagnesaemia is more prevalent in females and is associated with diabetic retinopathy and poor glycaemic control. Having a sufficient magnesium level may be associated with better glycaemic control and a reduced occurrence of complications.http://www.ijem.in/article.asp?issn=2230-8210;year=2022;volume=26;issue=6;spage=575;epage=580;aulast=Hamarshihdiabetes mellitusglycaemic controlhypomagnesaemiapalestine |
| spellingShingle | Mohammad Hamarshih Suha Hamshari Zaher Nazzal Farha Snobar Rawa Mletat Ola Abu-Mazen Beesan Maraqa Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study Indian Journal of Endocrinology and Metabolism diabetes mellitus glycaemic control hypomagnesaemia palestine |
| title | Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study |
| title_full | Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study |
| title_fullStr | Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study |
| title_full_unstemmed | Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study |
| title_short | Hypomagnesemia and poor glycemic control among type 2 diabetic patients: A cross-sectional study |
| title_sort | hypomagnesemia and poor glycemic control among type 2 diabetic patients a cross sectional study |
| topic | diabetes mellitus glycaemic control hypomagnesaemia palestine |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2022;volume=26;issue=6;spage=575;epage=580;aulast=Hamarshih |
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