Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum

OBJECTIVE: Plasma zinc levels and possible relationship with Helicobacter Pylori (HP) serology positivity in women with hyperemesis gravidarum (HEG) are studied in order to test hypothesis decreased zinc levels possibly induced by HP might have a pathogenic role in HEG. STUDY DESIGN: Thirty pregnant...

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Main Authors: Evrim Erdemoğlu, Mehmet Güney, Tuğçe Çimen, Tamer Mungan
Format: Article
Language:English
Published: Medical Network 2009-08-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:http://gorm.com.tr/index.php/GORM/article/view/404
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author Evrim Erdemoğlu
Mehmet Güney
Tuğçe Çimen
Tamer Mungan
author_facet Evrim Erdemoğlu
Mehmet Güney
Tuğçe Çimen
Tamer Mungan
author_sort Evrim Erdemoğlu
collection DOAJ
description OBJECTIVE: Plasma zinc levels and possible relationship with Helicobacter Pylori (HP) serology positivity in women with hyperemesis gravidarum (HEG) are studied in order to test hypothesis decreased zinc levels possibly induced by HP might have a pathogenic role in HEG. STUDY DESIGN: Thirty pregnant women with HEG and controls were enrolled into study. Zinc concentrations were determined by atomic absorption spectrophotometry. Specific serum antibodies directed against HP were measured. RESULTS: HP IgG antibodies were detected in 76.6% of HEG women and in 43.3% of controls (p<0.05). Mean of zinc level was 96.9±40.1 micromol/l and 80.9±16.6 micromol/l in HEG and controls, respectively (p>0.05). Zinc levels were not correlated either with helicobacter pylori serology or study groups (p>0.05). CONCLUSION: Serum zinc level is not altered by HEG and HP infection. There might be a possible association between HEG and HP, however there was no relation between HEG, HP and zinc.
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spelling doaj.art-fadaac69c7b841dcb84ae5d94fe612ba2023-02-15T16:17:37ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512009-08-01152336Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis GravidarumEvrim Erdemoğlu0Mehmet Güney1Tuğçe Çimen2Tamer Mungan3Department of Obstetrics and Gynecology Faculty of Medicine Süleyman Demirel University, IspartaDepartment of Obstetrics and Gynecology Faculty of Medicine Süleyman Demirel University, IspartaDepartment of Obstetrics and Gynecology Faculty of Medicine Süleyman Demirel University, IspartaDepartment of Obstetrics and Gynecology Faculty of Medicine Süleyman Demirel University, IspartaOBJECTIVE: Plasma zinc levels and possible relationship with Helicobacter Pylori (HP) serology positivity in women with hyperemesis gravidarum (HEG) are studied in order to test hypothesis decreased zinc levels possibly induced by HP might have a pathogenic role in HEG. STUDY DESIGN: Thirty pregnant women with HEG and controls were enrolled into study. Zinc concentrations were determined by atomic absorption spectrophotometry. Specific serum antibodies directed against HP were measured. RESULTS: HP IgG antibodies were detected in 76.6% of HEG women and in 43.3% of controls (p<0.05). Mean of zinc level was 96.9±40.1 micromol/l and 80.9±16.6 micromol/l in HEG and controls, respectively (p>0.05). Zinc levels were not correlated either with helicobacter pylori serology or study groups (p>0.05). CONCLUSION: Serum zinc level is not altered by HEG and HP infection. There might be a possible association between HEG and HP, however there was no relation between HEG, HP and zinc.http://gorm.com.tr/index.php/GORM/article/view/404Hyperemesis gravidarum, Zinc, Helicobacter pylori, Serology
spellingShingle Evrim Erdemoğlu
Mehmet Güney
Tuğçe Çimen
Tamer Mungan
Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
Gynecology Obstetrics & Reproductive Medicine
Hyperemesis gravidarum, Zinc, Helicobacter pylori, Serology
title Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
title_full Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
title_fullStr Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
title_full_unstemmed Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
title_short Serum Zinc Concentration and Helicobacter Pylori Serology in Hyperemesis Gravidarum
title_sort serum zinc concentration and helicobacter pylori serology in hyperemesis gravidarum
topic Hyperemesis gravidarum, Zinc, Helicobacter pylori, Serology
url http://gorm.com.tr/index.php/GORM/article/view/404
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AT mehmetguney serumzincconcentrationandhelicobacterpyloriserologyinhyperemesisgravidarum
AT tugcecimen serumzincconcentrationandhelicobacterpyloriserologyinhyperemesisgravidarum
AT tamermungan serumzincconcentrationandhelicobacterpyloriserologyinhyperemesisgravidarum