Cryptosporidium parvum upregulates miR-942-5p expression in HCT-8 cells via TLR2/TLR4-NF-κB signaling

Cryptosporidium parvum upregulates miR-942-5p expression in HCT-8 cells via TLR2/TLR4-NF-κB signaling

Abstract Background Micro (mi)RNAs are small noncoding RNA molecules that function in RNA silencing and post-transcriptional regulation of gene expression. This study investigated host miRNA activity in the innate immune response to Cryptosporidium parvum infection. Methods In vitro infection model...

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Bibliographic Details
Main Authors: Guiling Zhang, Yajun Zhang, Ziwen Niu, Chenrong Wang, Fujie Xie, Juanfeng Li, Sumei Zhang, Meng Qi, Fuchun Jian, Changshen Ning, Longxian Zhang, Rongjun Wang
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Parasites & Vectors
Subjects:
Cryptosporidium parvum
HCT-8
TLRs
NF-κB
miR-942-5p
Online Access:http://link.springer.com/article/10.1186/s13071-020-04312-x

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