Isoflavone-Enriched Soybean Leaves (Glycine Max) Alleviate Cognitive Impairment Induced by Ovariectomy and Modulate PI3K/Akt Signaling in the Hippocampus of C57BL6 Mice

Isoflavone-Enriched Soybean Leaves (Glycine Max) Alleviate Cognitive Impairment Induced by Ovariectomy and Modulate PI3K/Akt Signaling in the Hippocampus of C57BL6 Mice

(1) Background: The estrogen decline during perimenopause can induce various disorders, including cognitive impairment. Phytoestrogens, such as isoflavones, lignans, and coumestans, have been tried as a popular alternative to avoid the side effects of conventional hormone replacement therapy, but th...

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Bibliographic Details
Main Authors: Dae Young Yoo, Soonwoong Jung, Jae Soon Kang, Ji Hyeong Baek, Ki Hun Park, Dong Hoon Lee, Sang Soo Kang, Hyun Joon Kim
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Nutrients
Subjects:
menopause
phytoestrogen
isoflavone
cognition
ovariectomy
Online Access:https://www.mdpi.com/2072-6643/14/22/4753

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