Spinal astrocyte-derived interleukin-17A promotes pain hypersensitivity in bone cancer mice

Spinal microglia and astrocytes are both involved in neuropathic and inflammatory pain, which may display sexual dimorphism. Here, we demonstrate that the sustained activation of spinal astrocytes and astrocyte-derived interleukin (IL)-17A promotes the progression of mouse bone cancer pain without s...

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Bibliographic Details
Main Authors: Huizhu Liu, Xuejing Lv, Xin Zhao, Lanxing Yi, Ning Lv, Wendong Xu, Yuqiu Zhang
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524003812