STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
Experimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigat...
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Format: | Article |
Language: | Russian |
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LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/411 |
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author | T. A. Pankrusheva I. N. Maravina O. A. Medvedeva M. S. Chekmareva |
author_facet | T. A. Pankrusheva I. N. Maravina O. A. Medvedeva M. S. Chekmareva |
author_sort | T. A. Pankrusheva |
collection | DOAJ |
description | Experimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigated for studying of the antibiotic stability, when azithromycin is used in wet granulation tableting technology. Identifies the main technological characteristics of the granulates, the tablets are produced by compression and indicators of quality are studied. |
first_indexed | 2024-04-10T01:40:50Z |
format | Article |
id | doaj.art-fae455796df742f5a4fac01d69a442e0 |
institution | Directory Open Access Journal |
issn | 2305-2066 2658-5049 |
language | Russian |
last_indexed | 2025-03-14T11:45:31Z |
publishDate | 2019-01-01 |
publisher | LLC Center of Pharmaceutical Analytics (LLC «CPHA») |
record_format | Article |
series | Разработка и регистрация лекарственных средств |
spelling | doaj.art-fae455796df742f5a4fac01d69a442e02025-03-02T09:53:19ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01028488411STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCINT. A. Pankrusheva0I. N. Maravina1O. A. Medvedeva2M. S. Chekmareva3Kursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationExperimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigated for studying of the antibiotic stability, when azithromycin is used in wet granulation tableting technology. Identifies the main technological characteristics of the granulates, the tablets are produced by compression and indicators of quality are studied.https://www.pharmjournal.ru/jour/article/view/411azithromycinexcipientsgranulationantimicrobial activityoro-dispersible tablets |
spellingShingle | T. A. Pankrusheva I. N. Maravina O. A. Medvedeva M. S. Chekmareva STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN Разработка и регистрация лекарственных средств azithromycin excipients granulation antimicrobial activity oro-dispersible tablets |
title | STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN |
title_full | STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN |
title_fullStr | STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN |
title_full_unstemmed | STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN |
title_short | STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN |
title_sort | studies of the development of oro dispersible tablets with azithromycin |
topic | azithromycin excipients granulation antimicrobial activity oro-dispersible tablets |
url | https://www.pharmjournal.ru/jour/article/view/411 |
work_keys_str_mv | AT tapankrusheva studiesofthedevelopmentoforodispersibletabletswithazithromycin AT inmaravina studiesofthedevelopmentoforodispersibletabletswithazithromycin AT oamedvedeva studiesofthedevelopmentoforodispersibletabletswithazithromycin AT mschekmareva studiesofthedevelopmentoforodispersibletabletswithazithromycin |