STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN

Experimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigat...

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Main Authors: T. A. Pankrusheva, I. N. Maravina, O. A. Medvedeva, M. S. Chekmareva
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/411
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author T. A. Pankrusheva
I. N. Maravina
O. A. Medvedeva
M. S. Chekmareva
author_facet T. A. Pankrusheva
I. N. Maravina
O. A. Medvedeva
M. S. Chekmareva
author_sort T. A. Pankrusheva
collection DOAJ
description Experimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigated for studying of the antibiotic stability, when azithromycin is used in wet granulation tableting technology. Identifies the main technological characteristics of the granulates, the tablets are produced by compression and indicators of quality are studied.
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spelling doaj.art-fae455796df742f5a4fac01d69a442e02025-03-02T09:53:19ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01028488411STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCINT. A. Pankrusheva0I. N. Maravina1O. A. Medvedeva2M. S. Chekmareva3Kursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationKursk State Medical University of the Ministry of Health of the Russian FederationExperimental data on the development of composition and technology of oro-dispersible tablets with azithromycin. There is shown the study of sweet taste of the tablets masses, the production of tablets on the basis of their granulates. Antimicrobial properties of the tablet granulates are investigated for studying of the antibiotic stability, when azithromycin is used in wet granulation tableting technology. Identifies the main technological characteristics of the granulates, the tablets are produced by compression and indicators of quality are studied.https://www.pharmjournal.ru/jour/article/view/411azithromycinexcipientsgranulationantimicrobial activityoro-dispersible tablets
spellingShingle T. A. Pankrusheva
I. N. Maravina
O. A. Medvedeva
M. S. Chekmareva
STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
Разработка и регистрация лекарственных средств
azithromycin
excipients
granulation
antimicrobial activity
oro-dispersible tablets
title STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
title_full STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
title_fullStr STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
title_full_unstemmed STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
title_short STUDIES OF THE DEVELOPMENT OF ORO-DISPERSIBLE TABLETS WITH AZITHROMYCIN
title_sort studies of the development of oro dispersible tablets with azithromycin
topic azithromycin
excipients
granulation
antimicrobial activity
oro-dispersible tablets
url https://www.pharmjournal.ru/jour/article/view/411
work_keys_str_mv AT tapankrusheva studiesofthedevelopmentoforodispersibletabletswithazithromycin
AT inmaravina studiesofthedevelopmentoforodispersibletabletswithazithromycin
AT oamedvedeva studiesofthedevelopmentoforodispersibletabletswithazithromycin
AT mschekmareva studiesofthedevelopmentoforodispersibletabletswithazithromycin