Determining the temporal, dose, and composition effects of nutritional substrates in an in vitro model of intrahepatocellular triglyceride accumulation

Determining the temporal, dose, and composition effects of nutritional substrates in an in vitro model of intrahepatocellular triglyceride accumulation

Abstract Pathological accumulation of intrahepatic triglyceride underpins the early stages of nonalcoholic fatty liver disease (NAFLD) and can progress to fibrosis, cirrhosis, and cancer of the liver. Studies in humans suggest that consumption of a diet enriched in saturated compared to unsaturated...

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Bibliographic Details
Main Authors: Shilpa R. Nagarajan, Eloise Cross, Elspeth Johnson, Fabio Sanna, Lorna J. Daniels, David W. Ray, Leanne Hodson
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Physiological Reports
Subjects:
in vitro
liver
metabolism
saturated fatty acids
Online Access:https://doi.org/10.14814/phy2.15463

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