Young apple polyphenols postpone starch digestion in vitro and in vivo
Type II diabetes is largely related with hyperglycemia that can be controlled through inhibition the activities of carbohydrate-hydrolyzing enzymes by dietary polyphenols. This study aims to explore the effects of young apple polyphenols (YAP) on starch digestion in vitro and in vivo by acute and 1-...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2019-05-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464619301288 |
| _version_ | 1818953920415793152 |
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| author | Dan Li Lijun Sun Yongli Yang Zichao Wang Xi Yang Ting Zhao Tian Gong Li Zou Yurong Guo |
| author_facet | Dan Li Lijun Sun Yongli Yang Zichao Wang Xi Yang Ting Zhao Tian Gong Li Zou Yurong Guo |
| author_sort | Dan Li |
| collection | DOAJ |
| description | Type II diabetes is largely related with hyperglycemia that can be controlled through inhibition the activities of carbohydrate-hydrolyzing enzymes by dietary polyphenols. This study aims to explore the effects of young apple polyphenols (YAP) on starch digestion in vitro and in vivo by acute and 1-week intervention administrations using mice. It was found that YAP was able to inhibit the starch digestive enzymes including α-amylase and α-glucosidase, in which tannic acid and chlorogenic acid showed inhibition on α-amylase, and tannic acid and phlorizin showed inhibition on α-glucosidase. In addition, the levels of postprandial blood glucose and insulin were lowered by around 10% at a peak for the mice fed with combination of starch and YAP than that only fed with starch, which was observed for acute and 1-week administrations. Taken together, YAP may have potentials as a functional food in assisting prevention and alleviation of type II diabetes disease. |
| first_indexed | 2024-12-20T10:13:56Z |
| format | Article |
| id | doaj.art-fae6b8045f9d41daaaac434ec94203e1 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-12-20T10:13:56Z |
| publishDate | 2019-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-fae6b8045f9d41daaaac434ec94203e12022-12-21T19:44:07ZengElsevierJournal of Functional Foods1756-46462019-05-0156127135Young apple polyphenols postpone starch digestion in vitro and in vivoDan Li0Lijun Sun1Yongli Yang2Zichao Wang3Xi Yang4Ting Zhao5Tian Gong6Li Zou7Yurong Guo8College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, China; Corresponding authors.College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, ChinaShaanxi Product Quality Supervision and Inspection Research Institute, Xi’an 710000, Shaanxi Province, ChinaCollege of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi’an 710062, China; Corresponding authors.Type II diabetes is largely related with hyperglycemia that can be controlled through inhibition the activities of carbohydrate-hydrolyzing enzymes by dietary polyphenols. This study aims to explore the effects of young apple polyphenols (YAP) on starch digestion in vitro and in vivo by acute and 1-week intervention administrations using mice. It was found that YAP was able to inhibit the starch digestive enzymes including α-amylase and α-glucosidase, in which tannic acid and chlorogenic acid showed inhibition on α-amylase, and tannic acid and phlorizin showed inhibition on α-glucosidase. In addition, the levels of postprandial blood glucose and insulin were lowered by around 10% at a peak for the mice fed with combination of starch and YAP than that only fed with starch, which was observed for acute and 1-week administrations. Taken together, YAP may have potentials as a functional food in assisting prevention and alleviation of type II diabetes disease.http://www.sciencedirect.com/science/article/pii/S1756464619301288Young apple polyphenolsα-amylaseα-glucosidasePostprandial blood glucoseInsulin level |
| spellingShingle | Dan Li Lijun Sun Yongli Yang Zichao Wang Xi Yang Ting Zhao Tian Gong Li Zou Yurong Guo Young apple polyphenols postpone starch digestion in vitro and in vivo Journal of Functional Foods Young apple polyphenols α-amylase α-glucosidase Postprandial blood glucose Insulin level |
| title | Young apple polyphenols postpone starch digestion in vitro and in vivo |
| title_full | Young apple polyphenols postpone starch digestion in vitro and in vivo |
| title_fullStr | Young apple polyphenols postpone starch digestion in vitro and in vivo |
| title_full_unstemmed | Young apple polyphenols postpone starch digestion in vitro and in vivo |
| title_short | Young apple polyphenols postpone starch digestion in vitro and in vivo |
| title_sort | young apple polyphenols postpone starch digestion in vitro and in vivo |
| topic | Young apple polyphenols α-amylase α-glucosidase Postprandial blood glucose Insulin level |
| url | http://www.sciencedirect.com/science/article/pii/S1756464619301288 |
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