Valproate induced subclinical hypothyroidism in children with epilepsy
Stroke remains a leading cause of disability and mortality all over the world despite the efforts made towards improving treatment. Most of the clinical studies have not shown significant beneficial effects in the evaluation of various molecules for their neuroprotection and neurorecovery promoting...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2013-12-01
|
| Series: | Romanian Journal of Neurology |
| Subjects: | |
| Online Access: | https://rjn.com.ro/articles/2013.4/RJN_2013_4_Art-04.pdf |
| _version_ | 1811205017746538496 |
|---|---|
| author | Raluca Teleanu Margarita Matei Magdalena Sandu Smaranda Nita |
| author_facet | Raluca Teleanu Margarita Matei Magdalena Sandu Smaranda Nita |
| author_sort | Raluca Teleanu |
| collection | DOAJ |
| description | Stroke remains a leading cause of disability and mortality all over the world despite the efforts made towards improving treatment. Most of the clinical studies have not shown significant beneficial effects in the evaluation of various molecules for their neuroprotection and neurorecovery promoting properties. The new concept of multimodal, pleiotropic drugs has opened new perspectives in this field. This review focuses on clinical stroke studies with biologically active molecules such as erythropoietin, granulocyte-colony stimulating factor and Cerebrolysin. |
| first_indexed | 2024-04-12T03:23:30Z |
| format | Article |
| id | doaj.art-fae6db64cf8e419793c8f960ec871359 |
| institution | Directory Open Access Journal |
| issn | 1843-8148 2069-6094 |
| language | English |
| last_indexed | 2024-04-12T03:23:30Z |
| publishDate | 2013-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Journal of Neurology |
| spelling | doaj.art-fae6db64cf8e419793c8f960ec8713592022-12-22T03:49:48ZengAmaltea Medical Publishing HouseRomanian Journal of Neurology1843-81482069-60942013-12-0112418318410.37897/RJN.2013.4.4Valproate induced subclinical hypothyroidism in children with epilepsyRaluca Teleanu0Margarita Matei1Magdalena Sandu2Smaranda Nita3Department of Pediatric Neurology, “Dr. Victor Gomoiu” Children’s Hospital, Bucharest; “Carol Davila” University of Medicine and Pharmacy, BucharestEndocrinology Ambulatory, “Dr. Victor Gomoiu” Children’s Hospital, Bucharest“Carol Davila” University of Medicine and Pharmacy, BucharestDepartment of Pediatric Neurology, “Dr. Victor Gomoiu” Children’s Hospital, BucharestStroke remains a leading cause of disability and mortality all over the world despite the efforts made towards improving treatment. Most of the clinical studies have not shown significant beneficial effects in the evaluation of various molecules for their neuroprotection and neurorecovery promoting properties. The new concept of multimodal, pleiotropic drugs has opened new perspectives in this field. This review focuses on clinical stroke studies with biologically active molecules such as erythropoietin, granulocyte-colony stimulating factor and Cerebrolysin.https://rjn.com.ro/articles/2013.4/RJN_2013_4_Art-04.pdfneuroprotectionneurorecoverymultimodalpleiotropic drugs |
| spellingShingle | Raluca Teleanu Margarita Matei Magdalena Sandu Smaranda Nita Valproate induced subclinical hypothyroidism in children with epilepsy Romanian Journal of Neurology neuroprotection neurorecovery multimodal pleiotropic drugs |
| title | Valproate induced subclinical hypothyroidism in children with epilepsy |
| title_full | Valproate induced subclinical hypothyroidism in children with epilepsy |
| title_fullStr | Valproate induced subclinical hypothyroidism in children with epilepsy |
| title_full_unstemmed | Valproate induced subclinical hypothyroidism in children with epilepsy |
| title_short | Valproate induced subclinical hypothyroidism in children with epilepsy |
| title_sort | valproate induced subclinical hypothyroidism in children with epilepsy |
| topic | neuroprotection neurorecovery multimodal pleiotropic drugs |
| url | https://rjn.com.ro/articles/2013.4/RJN_2013_4_Art-04.pdf |
| work_keys_str_mv | AT ralucateleanu valproateinducedsubclinicalhypothyroidisminchildrenwithepilepsy AT margaritamatei valproateinducedsubclinicalhypothyroidisminchildrenwithepilepsy AT magdalenasandu valproateinducedsubclinicalhypothyroidisminchildrenwithepilepsy AT smarandanita valproateinducedsubclinicalhypothyroidisminchildrenwithepilepsy |