HLA-C dysregulation as a possible mechanism of immune evasion in SARS-CoV-2 and other RNA-virus infections

HLA-C dysregulation as a possible mechanism of immune evasion in SARS-CoV-2 and other RNA-virus infections

One of the mechanisms by which viruses can evade the host’s immune system is to modify the host’s DNA methylation pattern. This work aims to investigate the DNA methylation and gene expression profile of COVID-19 patients, divided into symptomatic and asymptomatic, and healthy controls, focusing on...

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Bibliographic Details
Main Authors: Eleonora Loi, Loredana Moi, Paola Cabras, Giulia Arduino, Giulia Costanzo, Stefano Del Giacco, Henry A. Erlich, Davide Firinu, Aldo Caddori, Patrizia Zavattari
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
DNA methylation
HLA-C
gene expression
enhancer transcriptional regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1011829/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1011829/full

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