Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials
Objective: Endourological treatment is associated with a risk of postoperative febrile urinary tract infections and sepsis. The aim of this study was to review the reported rate of infectious complications in relation to the type and modality of the endourologic procedure. Methods: This systematic...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2022-03-01
|
| Series: | Archivio Italiano di Urologia e Andrologia |
| Subjects: | |
| Online Access: | https://www.pagepressjournals.org/index.php/aiua/article/view/10486 |
| _version_ | 1819179014352273408 |
|---|---|
| author | Rawa Bapir Kamran Hassan Bhatti Ahmed Eliwa Herney Andrés García-Perdomo Nazim Gherabi Derek Hennessey Panagiotis Mourmouris Adama Ouattara Gianpaolo Perletti Joseph Philipraj Alberto Trinchieri Noor Buchholz |
| author_facet | Rawa Bapir Kamran Hassan Bhatti Ahmed Eliwa Herney Andrés García-Perdomo Nazim Gherabi Derek Hennessey Panagiotis Mourmouris Adama Ouattara Gianpaolo Perletti Joseph Philipraj Alberto Trinchieri Noor Buchholz |
| author_sort | Rawa Bapir |
| collection | DOAJ |
| description |
Objective: Endourological treatment is associated with a risk of postoperative febrile urinary tract infections and sepsis. The aim of this study was to review the reported rate of infectious complications in relation to the type and modality of the endourologic procedure.
Methods: This systematic review was conducted in accordance with the PRISMA guidelines. Two electronic databases (PubMed and EMBASE) were searched. Out of 243 articles retrieved we included 49 studies after full-text evaluation.
Results: Random-effects meta-analysis demonstrated that retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) were associated with not significantly different odds of getting fever (OR = 1.54, 95% CI: 0.99 to 2.39; p = 0.06) or sepsis (OR = 1.52, 95% CI: 0.37 to 6.20, p = 0.56). The odds of getting fever were not significantly different for mini PCNL compared to standard PCNL (OR = 1.11, 95% CI: 0.85 to 1.44; p = 0.45) and for tubeless PCNL compared to standard PCNL (OR = 1.34 95% CI: 0.61 to 2.91, p = 0.47). However, the odds for fever after PCNL with suctioning sheath were lower than the corresponding odds for standard PCNL (OR = 0.37, 95% CI: 0.20 to 0.70, p = 0.002). The odds of getting fever after PCNL with perioperative prophylaxis were not different from the corresponding odds after PCNL with perioperative prophylaxis plus a short oral antibiotic course (before or after the procedure) (OR = 1.31, 95% CI: 0.71 to 2.39, p = 0.38).
Conclusions: The type of endourological procedure does not appear to be decisive in the onset of infectious complications, although the prevention of high intrarenal pressure during the procedure could be crucial in defining the risk of infectious complications.
on behalf of U-merge Ltd. (Urology for emerging countries), London-Athens-Dubai
|
| first_indexed | 2024-12-22T21:51:42Z |
| format | Article |
| id | doaj.art-fae9daa6b10345c7a825025c3ffb480e |
| institution | Directory Open Access Journal |
| issn | 1124-3562 2282-4197 |
| language | English |
| last_indexed | 2024-12-22T21:51:42Z |
| publishDate | 2022-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Archivio Italiano di Urologia e Andrologia |
| spelling | doaj.art-fae9daa6b10345c7a825025c3ffb480e2022-12-21T18:11:21ZengPAGEPress PublicationsArchivio Italiano di Urologia e Andrologia1124-35622282-41972022-03-0194110.4081/aiua.2022.1.97Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trialsRawa Bapir0Kamran Hassan Bhatti1Ahmed Eliwa2Herney Andrés García-Perdomo3Nazim Gherabi4Derek Hennessey5Panagiotis Mourmouris6Adama Ouattara7Gianpaolo Perletti8Joseph Philipraj9Alberto Trinchieri10Noor Buchholz11Smart Health Tower, Sulaymaniyah, Kurdistan regionUrology Department, HMC, Hamad Medical CorporationDepartment of Urology, Zagazig University, Zagazig, SharkiaUniversidad del Valle, CaliFaculty of Medicine Algiers 1, AlgiersDepartment of Urology, Mercy University Hospital, Cork2nd Department of Urology, National and Kapodistrian University of Athens, Sismanoglio Hospital, AthensDivision of Urology, Souro Sanou University Teaching Hospital, Bobo-DioulassoDepartment of Biotechnology and Life Sciences, Section of Medical and Surgical Sciences, University of Insubria, Varese, Italy; Faculty of Medicine and Medical Sciences, Ghent UniversityFaculty of Medicine and Medical Sciences, Ghent UniversityUrology School, University of MilanDepartment of Urology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry Objective: Endourological treatment is associated with a risk of postoperative febrile urinary tract infections and sepsis. The aim of this study was to review the reported rate of infectious complications in relation to the type and modality of the endourologic procedure. Methods: This systematic review was conducted in accordance with the PRISMA guidelines. Two electronic databases (PubMed and EMBASE) were searched. Out of 243 articles retrieved we included 49 studies after full-text evaluation. Results: Random-effects meta-analysis demonstrated that retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PCNL) were associated with not significantly different odds of getting fever (OR = 1.54, 95% CI: 0.99 to 2.39; p = 0.06) or sepsis (OR = 1.52, 95% CI: 0.37 to 6.20, p = 0.56). The odds of getting fever were not significantly different for mini PCNL compared to standard PCNL (OR = 1.11, 95% CI: 0.85 to 1.44; p = 0.45) and for tubeless PCNL compared to standard PCNL (OR = 1.34 95% CI: 0.61 to 2.91, p = 0.47). However, the odds for fever after PCNL with suctioning sheath were lower than the corresponding odds for standard PCNL (OR = 0.37, 95% CI: 0.20 to 0.70, p = 0.002). The odds of getting fever after PCNL with perioperative prophylaxis were not different from the corresponding odds after PCNL with perioperative prophylaxis plus a short oral antibiotic course (before or after the procedure) (OR = 1.31, 95% CI: 0.71 to 2.39, p = 0.38). Conclusions: The type of endourological procedure does not appear to be decisive in the onset of infectious complications, although the prevention of high intrarenal pressure during the procedure could be crucial in defining the risk of infectious complications. on behalf of U-merge Ltd. (Urology for emerging countries), London-Athens-Dubai https://www.pagepressjournals.org/index.php/aiua/article/view/10486Kidney calculiPercutaneous nephrolithotomyRetrograde intrarenal surgeryUreteroscopyLithotripsySystemic inflammatory response syndrome |
| spellingShingle | Rawa Bapir Kamran Hassan Bhatti Ahmed Eliwa Herney Andrés García-Perdomo Nazim Gherabi Derek Hennessey Panagiotis Mourmouris Adama Ouattara Gianpaolo Perletti Joseph Philipraj Alberto Trinchieri Noor Buchholz Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials Archivio Italiano di Urologia e Andrologia Kidney calculi Percutaneous nephrolithotomy Retrograde intrarenal surgery Ureteroscopy Lithotripsy Systemic inflammatory response syndrome |
| title | Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials |
| title_full | Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials |
| title_fullStr | Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials |
| title_full_unstemmed | Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials |
| title_short | Infectious complications of endourological treatment of kidney stones: A meta-analysis of randomized clinical trials |
| title_sort | infectious complications of endourological treatment of kidney stones a meta analysis of randomized clinical trials |
| topic | Kidney calculi Percutaneous nephrolithotomy Retrograde intrarenal surgery Ureteroscopy Lithotripsy Systemic inflammatory response syndrome |
| url | https://www.pagepressjournals.org/index.php/aiua/article/view/10486 |
| work_keys_str_mv | AT rawabapir infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT kamranhassanbhatti infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT ahmedeliwa infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT herneyandresgarciaperdomo infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT nazimgherabi infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT derekhennessey infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT panagiotismourmouris infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT adamaouattara infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT gianpaoloperletti infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT josephphilipraj infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT albertotrinchieri infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials AT noorbuchholz infectiouscomplicationsofendourologicaltreatmentofkidneystonesametaanalysisofrandomizedclinicaltrials |