Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma
Background/Aim. Refractory glaucoma is glaucoma resistant to conventional management (maximally tolerated medical therapy, one or more glaucoma surgeries) and glaucoma in cases of neovascularisation after panretinal photocoagulation or cryoablation. The aim of the study was to determine the...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2015-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501016C.pdf |
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| author | Čanadanović Vladimir Tušek-Lješević Ljiljana Miljković Aleksandar Barišić Sava Bedov Tatjana Babić Nikola |
| author_facet | Čanadanović Vladimir Tušek-Lješević Ljiljana Miljković Aleksandar Barišić Sava Bedov Tatjana Babić Nikola |
| author_sort | Čanadanović Vladimir |
| collection | DOAJ |
| description | Background/Aim. Refractory glaucoma is glaucoma resistant to conventional
management (maximally tolerated medical therapy, one or more glaucoma
surgeries) and glaucoma in cases of neovascularisation after panretinal
photocoagulation or cryoablation. The aim of the study was to determine the
intraocular pressure (IOP) lowering efficacy of transscleral diode laser
cyclophotocoagulation (DCPC) treatment in the management of pain and IOP in
patients with refractory glaucoma. Methods. This nonrandomized, retrospective
study, included 95 patients (95 eyes) with refractory glaucoma treated at the
University Eye Clinic, Clinical Center of Vojvodina, Novi Sad, Serbia,
between November 2007 and November 2012 in accordance with the established
protocols (16-18 spots, 270°, up to 5J of energy). All the eyes were treated
with transscleral DCPC (Iris Medical OcuLight SLx, Iridex Co, Mountain View,
USA). Patient's symptoms, bests corrected visual acuity and IOP were recorded
7 days, and 1, 3 and 6 months after the DCPC treatment. Results. Out of 95
patients (95 eyes) enrolled in this study 24 (25.2%) were with primary (the
group I), and 71 (74.5%) with secondary (the group II) glaucoma. The mean
baseline IOP in these two groups was similar: 36.08 ± 8.39 mmHg for the first
group and 37.36 ± 8.19 mmHg in the second group. Measurement of the mean IOP
in the group I showed the following results: on the day 7 it was 13.96 ± 8.30
mmHg (62.1% decrease of the baseline value), on the day 30 it was 18.44 ±
8.85 mmHg (48.9% decrease regarding the baseline value), after 3 months it
was 22.44 ± 7.36 mmHg (37.8% decrease regarding the baseline value), and
after 6 months it was 25.92 ± 7.65 mmHg (28.2% decrease regarding the
baseline value). Measurement of IOP in the group II showed the following
results: on the day 7 it was 15.77 ± 9.73 mmHg (57.8% decrease of the
baseline value), on the day 30 it was 20.14 ± 10.20 mmHg (46.1% decrease
regarding the baseline value), after 3 months it was 23.46 ± 9.83 mmHg (37.2%
decrease regarding the baseline value) and after 6 months it was 27.23 ± 9.87
mmHg (27.2% decrease regarding the baseline value). Pain was the main symptom
in 70 (73.6%) patients before the treatment and it persisted in only 4 (4.2%)
of our patients. Other complaints (burning, stinging, foreign body sensation)
were experienced by 39 (41%) of the patients, postoperatively. A total of 52
(54.7%) patients had no complaints after the treatment. Conclusion. Our study
confirmed that transscleral DCPC is a useful, effective and safe procedure
with predictable amount of IOP decrease, which makes it the treatment of
choice for refractory glaucoma. |
| first_indexed | 2024-04-12T13:55:25Z |
| format | Article |
| id | doaj.art-faeacbb51a3741699db11f0423b1862e |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-04-12T13:55:25Z |
| publishDate | 2015-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-faeacbb51a3741699db11f0423b1862e2022-12-22T03:30:24ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502015-01-01721162010.2298/VSP1501016C0042-84501501016CEffect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucomaČanadanović Vladimir0Tušek-Lješević Ljiljana1Miljković Aleksandar2Barišić Sava3Bedov Tatjana4Babić Nikola5Clinical Center of Vojvodina, Eye Clinic, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Eye Clinic, Novi SadClinical Center of Vojvodina, Eye Clinic, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Eye Clinic, Novi SadClinical Center of Vojvodina, Eye Clinic, Novi Sad + Faculty of Medicine, Novi SadClinical Center of Vojvodina, Eye Clinic, Novi Sad + Faculty of Medicine, Novi SadBackground/Aim. Refractory glaucoma is glaucoma resistant to conventional management (maximally tolerated medical therapy, one or more glaucoma surgeries) and glaucoma in cases of neovascularisation after panretinal photocoagulation or cryoablation. The aim of the study was to determine the intraocular pressure (IOP) lowering efficacy of transscleral diode laser cyclophotocoagulation (DCPC) treatment in the management of pain and IOP in patients with refractory glaucoma. Methods. This nonrandomized, retrospective study, included 95 patients (95 eyes) with refractory glaucoma treated at the University Eye Clinic, Clinical Center of Vojvodina, Novi Sad, Serbia, between November 2007 and November 2012 in accordance with the established protocols (16-18 spots, 270°, up to 5J of energy). All the eyes were treated with transscleral DCPC (Iris Medical OcuLight SLx, Iridex Co, Mountain View, USA). Patient's symptoms, bests corrected visual acuity and IOP were recorded 7 days, and 1, 3 and 6 months after the DCPC treatment. Results. Out of 95 patients (95 eyes) enrolled in this study 24 (25.2%) were with primary (the group I), and 71 (74.5%) with secondary (the group II) glaucoma. The mean baseline IOP in these two groups was similar: 36.08 ± 8.39 mmHg for the first group and 37.36 ± 8.19 mmHg in the second group. Measurement of the mean IOP in the group I showed the following results: on the day 7 it was 13.96 ± 8.30 mmHg (62.1% decrease of the baseline value), on the day 30 it was 18.44 ± 8.85 mmHg (48.9% decrease regarding the baseline value), after 3 months it was 22.44 ± 7.36 mmHg (37.8% decrease regarding the baseline value), and after 6 months it was 25.92 ± 7.65 mmHg (28.2% decrease regarding the baseline value). Measurement of IOP in the group II showed the following results: on the day 7 it was 15.77 ± 9.73 mmHg (57.8% decrease of the baseline value), on the day 30 it was 20.14 ± 10.20 mmHg (46.1% decrease regarding the baseline value), after 3 months it was 23.46 ± 9.83 mmHg (37.2% decrease regarding the baseline value) and after 6 months it was 27.23 ± 9.87 mmHg (27.2% decrease regarding the baseline value). Pain was the main symptom in 70 (73.6%) patients before the treatment and it persisted in only 4 (4.2%) of our patients. Other complaints (burning, stinging, foreign body sensation) were experienced by 39 (41%) of the patients, postoperatively. A total of 52 (54.7%) patients had no complaints after the treatment. Conclusion. Our study confirmed that transscleral DCPC is a useful, effective and safe procedure with predictable amount of IOP decrease, which makes it the treatment of choice for refractory glaucoma.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501016C.pdfophthalmologic surgical proceduresglaucomalaser coagulationlasersintraocular pressuretreatment outcome |
| spellingShingle | Čanadanović Vladimir Tušek-Lješević Ljiljana Miljković Aleksandar Barišić Sava Bedov Tatjana Babić Nikola Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma Vojnosanitetski Pregled ophthalmologic surgical procedures glaucoma laser coagulation lasers intraocular pressure treatment outcome |
| title | Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| title_full | Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| title_fullStr | Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| title_full_unstemmed | Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| title_short | Effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| title_sort | effect of diode laser cyclophotocoagulation in treatment of patients with refractory glaucoma |
| topic | ophthalmologic surgical procedures glaucoma laser coagulation lasers intraocular pressure treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501501016C.pdf |
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