The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study
BackgroundEsophageal pressure (Pes) can be used as a reliable surrogate for pleural pressure, especially in critically ill patients requiring personalized mechanical ventilation strategies. How to choose the proper esophageal balloon filling volume and then find the optimal value of esophageal press...
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Frontiers Media S.A.
2022-12-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.986982/full |
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| author | Jing Jiang Jing Jiang Longxiang Su Wei Cheng Chunfu Wang Chunfu Wang Xi Rui Bo Tang Hongmin Zhang Huaiwu He Yun Long |
| author_facet | Jing Jiang Jing Jiang Longxiang Su Wei Cheng Chunfu Wang Chunfu Wang Xi Rui Bo Tang Hongmin Zhang Huaiwu He Yun Long |
| author_sort | Jing Jiang |
| collection | DOAJ |
| description | BackgroundEsophageal pressure (Pes) can be used as a reliable surrogate for pleural pressure, especially in critically ill patients requiring personalized mechanical ventilation strategies. How to choose the proper esophageal balloon filling volume and then find the optimal value of esophageal pressure remains a challenge. The study aimed to assess the feasibility of catheters for Pes monitoring in mechanically ventilated patients.Materials and methodsTwelve patients under pressure-controlled mechanical ventilation were included in this study. Raw esophageal pressure was recorded at different balloon filling volumes. Then, the P-V curves were determined. VWORK was the intermediate linear section on the end-expiratory P-V curve, and VBEST was the filling volume providing the maximum difference between Pes at end-inspiration and end-expiration. The raw value of Pes was recorded, and the calibrated values of Pes were calculated by calculating the esophageal wall pressure (Pew) and esophageal elastance (Ees).ResultsTwenty-four series of Pes measurements were performed. The mean VMIN and VMAX were 2.17 ± 0.49 ml (range, 1.0–3.0 ml) and 6.79 ± 0.83 ml (range, 5.0–9.0 ml), respectively, whereas VBEST was 4.69 ± 0.16 ml (range, 2.0–8.0 ml). Ees was 1.35 ± 0.51 cm H2O/ml (range, 0.26–2.38 cm H2O/ml). The estimated Pew at VBEST was 3.16 ± 2.19 cm H2O (range, 0–7.97 cm H2O). Patients with a body mass index (BMI) ≥ 25 kg/m2 had a significantly lower VMAX (5.88 [5.25–6] vs. 7.25 [7–8] ml, p = 0.006) and a significantly lower VBEST (3.69 [2.5–4.38] vs. 5.19 [4–6] ml, p = 0.036) than patients with a BMI < 25 kg/m2. Patients with positive end-expiratory pressure (PEEP) ≥ 10 cm H2O had a lower VMIN and VBEST than patients with PEEP < 10 cm H2O, P > 0.05. Patients in the supine position had a higher esophageal pressure than those in the prone position with the same balloon filling volume.ConclusionsCalibration of esophageal pressure to identify the best filling volume of esophageal balloon catheters is feasible. The esophageal pressure can be influenced by BMI, PEEP, and position. It is necessary to titrate the optimal inflation volume again when the PEEP values or the positions change. |
| first_indexed | 2024-04-12T00:42:20Z |
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| spelling | doaj.art-faeb9d08b67e4d678530d44fbe530abc2022-12-22T03:54:58ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-12-01910.3389/fmed.2022.986982986982The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical studyJing Jiang0Jing Jiang1Longxiang Su2Wei Cheng3Chunfu Wang4Chunfu Wang5Xi Rui6Bo Tang7Hongmin Zhang8Huaiwu He9Yun Long10Department of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Chongqing General Hospital, Chongqing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi’an, Shaanxi, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaDepartment of Critical Care Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, State Key Laboratory of Complex Severe and Rare Disease, Peking Union Medical College Hospital, Beijing, ChinaBackgroundEsophageal pressure (Pes) can be used as a reliable surrogate for pleural pressure, especially in critically ill patients requiring personalized mechanical ventilation strategies. How to choose the proper esophageal balloon filling volume and then find the optimal value of esophageal pressure remains a challenge. The study aimed to assess the feasibility of catheters for Pes monitoring in mechanically ventilated patients.Materials and methodsTwelve patients under pressure-controlled mechanical ventilation were included in this study. Raw esophageal pressure was recorded at different balloon filling volumes. Then, the P-V curves were determined. VWORK was the intermediate linear section on the end-expiratory P-V curve, and VBEST was the filling volume providing the maximum difference between Pes at end-inspiration and end-expiration. The raw value of Pes was recorded, and the calibrated values of Pes were calculated by calculating the esophageal wall pressure (Pew) and esophageal elastance (Ees).ResultsTwenty-four series of Pes measurements were performed. The mean VMIN and VMAX were 2.17 ± 0.49 ml (range, 1.0–3.0 ml) and 6.79 ± 0.83 ml (range, 5.0–9.0 ml), respectively, whereas VBEST was 4.69 ± 0.16 ml (range, 2.0–8.0 ml). Ees was 1.35 ± 0.51 cm H2O/ml (range, 0.26–2.38 cm H2O/ml). The estimated Pew at VBEST was 3.16 ± 2.19 cm H2O (range, 0–7.97 cm H2O). Patients with a body mass index (BMI) ≥ 25 kg/m2 had a significantly lower VMAX (5.88 [5.25–6] vs. 7.25 [7–8] ml, p = 0.006) and a significantly lower VBEST (3.69 [2.5–4.38] vs. 5.19 [4–6] ml, p = 0.036) than patients with a BMI < 25 kg/m2. Patients with positive end-expiratory pressure (PEEP) ≥ 10 cm H2O had a lower VMIN and VBEST than patients with PEEP < 10 cm H2O, P > 0.05. Patients in the supine position had a higher esophageal pressure than those in the prone position with the same balloon filling volume.ConclusionsCalibration of esophageal pressure to identify the best filling volume of esophageal balloon catheters is feasible. The esophageal pressure can be influenced by BMI, PEEP, and position. It is necessary to titrate the optimal inflation volume again when the PEEP values or the positions change.https://www.frontiersin.org/articles/10.3389/fmed.2022.986982/fullesophageal pressureesophageal balloon catheterballoon filling volumemechanical ventilationcalibration |
| spellingShingle | Jing Jiang Jing Jiang Longxiang Su Wei Cheng Chunfu Wang Chunfu Wang Xi Rui Bo Tang Hongmin Zhang Huaiwu He Yun Long The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study Frontiers in Medicine esophageal pressure esophageal balloon catheter balloon filling volume mechanical ventilation calibration |
| title | The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study |
| title_full | The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study |
| title_fullStr | The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study |
| title_full_unstemmed | The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study |
| title_short | The calibration of esophageal pressure by proper esophageal balloon filling volume: A clinical study |
| title_sort | calibration of esophageal pressure by proper esophageal balloon filling volume a clinical study |
| topic | esophageal pressure esophageal balloon catheter balloon filling volume mechanical ventilation calibration |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.986982/full |
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