What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic?
Initial reports suggested that kidney involvement after coronavirus disease 19 (COVID-19) infection was uncommon, but this premise appears to be incorrect. Acute kidney injury can occur through various mechanisms and complicate the course of up to 25% of patients with COVID-19 hospitalized in our In...
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| Format: | Article |
| Language: | English |
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Permanyer
2022-01-01
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| Series: | Revista de Investigación Clínica |
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| Online Access: | https://www.clinicalandtranslationalinvestigation.com/frame_esp.php?id=442 |
| _version_ | 1797979212415500288 |
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| author | Noemí Del Toro-Cisneros Adrián E. Caballero-Islas Juan C. Ramírez-Sandoval Juan M. Mejía-Vilet Mauricio Arvizu-Hernández Gustavo Casas-Aparicio Jonathan Chávez-Iñiguez Lilia M. Rizo-Topete Olynka Vega-Vega |
| author_facet | Noemí Del Toro-Cisneros Adrián E. Caballero-Islas Juan C. Ramírez-Sandoval Juan M. Mejía-Vilet Mauricio Arvizu-Hernández Gustavo Casas-Aparicio Jonathan Chávez-Iñiguez Lilia M. Rizo-Topete Olynka Vega-Vega |
| author_sort | Noemí Del Toro-Cisneros |
| collection | DOAJ |
| description | Initial reports suggested that kidney involvement after coronavirus disease 19 (COVID-19) infection was uncommon, but this premise appears to be incorrect. Acute kidney injury can occur through various mechanisms and complicate the course of up to 25% of patients with COVID-19 hospitalized in our Institution, and of over 50% of those on invasive mechanical ventilation. Mechanisms of injury include direct kidney injury and predominantly tubular, although glomerular injury has been reported, and resulting from severe hypoxic respiratory failure, secondary infection, and exposure to nephrotoxic drugs. The mainstay of treatment remains the prevention of progressive kidney damage and, in some cases, the use of renal replacement therapy. Although the use of blood purification techniques has been proposed as a potential treatment, results to date have not been conclusive. In this manuscript, the mechanisms of kidney injury by COVID-19, risk factors, and the mainstays of treatment are reviewed.
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| first_indexed | 2024-04-11T05:35:20Z |
| format | Article |
| id | doaj.art-faf0fdfd5ba44bb298b17b57c7afae04 |
| institution | Directory Open Access Journal |
| issn | 0034-8376 2564-8896 |
| language | English |
| last_indexed | 2024-04-11T05:35:20Z |
| publishDate | 2022-01-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Revista de Investigación Clínica |
| spelling | doaj.art-faf0fdfd5ba44bb298b17b57c7afae042022-12-22T13:59:01ZengPermanyerRevista de Investigación Clínica0034-83762564-88962022-01-0174610.24875/RIC.22000146What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic?Noemí Del Toro-Cisneros0Adrián E. Caballero-Islas1Juan C. Ramírez-Sandoval2Juan M. Mejía-Vilet3Mauricio Arvizu-Hernández4Gustavo Casas-Aparicio5Jonathan Chávez-Iñiguez6Lilia M. Rizo-Topete7Olynka Vega-Vega8Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoResearch Center for Infectious Diseases, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City, MexicoNephrology Service, Hospital Civil de Guadalajara Fray Antonio Alcalde, University of Guadalajara Health Sciences Center, Guadalajara, Jal., MexicoDivision of Nephrology, Hospital Universitario José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, NL., MexicoDepartment of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, MexicoInitial reports suggested that kidney involvement after coronavirus disease 19 (COVID-19) infection was uncommon, but this premise appears to be incorrect. Acute kidney injury can occur through various mechanisms and complicate the course of up to 25% of patients with COVID-19 hospitalized in our Institution, and of over 50% of those on invasive mechanical ventilation. Mechanisms of injury include direct kidney injury and predominantly tubular, although glomerular injury has been reported, and resulting from severe hypoxic respiratory failure, secondary infection, and exposure to nephrotoxic drugs. The mainstay of treatment remains the prevention of progressive kidney damage and, in some cases, the use of renal replacement therapy. Although the use of blood purification techniques has been proposed as a potential treatment, results to date have not been conclusive. In this manuscript, the mechanisms of kidney injury by COVID-19, risk factors, and the mainstays of treatment are reviewed. https://www.clinicalandtranslationalinvestigation.com/frame_esp.php?id=442Acute kidney injury. Coronavirus disease 19. Renal replacement therapy. Blood purification techniques. Cytokines. |
| spellingShingle | Noemí Del Toro-Cisneros Adrián E. Caballero-Islas Juan C. Ramírez-Sandoval Juan M. Mejía-Vilet Mauricio Arvizu-Hernández Gustavo Casas-Aparicio Jonathan Chávez-Iñiguez Lilia M. Rizo-Topete Olynka Vega-Vega What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? Revista de Investigación Clínica Acute kidney injury. Coronavirus disease 19. Renal replacement therapy. Blood purification techniques. Cytokines. |
| title | What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? |
| title_full | What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? |
| title_fullStr | What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? |
| title_full_unstemmed | What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? |
| title_short | What did we learn about coronavirus disease-19-associated acute kidney injury during the pandemic? |
| title_sort | what did we learn about coronavirus disease 19 associated acute kidney injury during the pandemic |
| topic | Acute kidney injury. Coronavirus disease 19. Renal replacement therapy. Blood purification techniques. Cytokines. |
| url | https://www.clinicalandtranslationalinvestigation.com/frame_esp.php?id=442 |
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