Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study
Objectives To quantify direct costs and healthcare resource utilisation (HCRU) associated with acute COVID-19 in adults in England.Design Population-based retrospective cohort study using Clinical Practice Research Datalink Aurum primary care electronic medical records linked to Hospital Episode Sta...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-12-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/12/e075495.full |
| _version_ | 1797370537195864064 |
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| author | Carmen Tsang Robert Wood Tendai Mugwagwa Kiran K Rai Jingyan Yang Theo Tritton Jennifer L Nguyen Kathleen Michelle Andersen Maya Reimbaeva Leah J McGrath Poppy Payne Bethany Emma Backhouse Diana Mendes Rebecca Butfield Kevin Naicker Mary Araghi |
| author_facet | Carmen Tsang Robert Wood Tendai Mugwagwa Kiran K Rai Jingyan Yang Theo Tritton Jennifer L Nguyen Kathleen Michelle Andersen Maya Reimbaeva Leah J McGrath Poppy Payne Bethany Emma Backhouse Diana Mendes Rebecca Butfield Kevin Naicker Mary Araghi |
| author_sort | Carmen Tsang |
| collection | DOAJ |
| description | Objectives To quantify direct costs and healthcare resource utilisation (HCRU) associated with acute COVID-19 in adults in England.Design Population-based retrospective cohort study using Clinical Practice Research Datalink Aurum primary care electronic medical records linked to Hospital Episode Statistics secondary care administrative data.Setting Patients registered to primary care practices in England.Population 1 706 368 adults with a positive SARS-CoV-2 PCR or antigen test from August 2020 to January 2022 were included; 13 105 within the hospitalised cohort indexed between August 2020 and March 2021, and 1 693 263 within the primary care cohort indexed between August 2020 and January 2022. Patients with a COVID-19-related hospitalisation within 84 days of a positive test were included in the hospitalised cohort.Main outcome measures Primary and secondary care HCRU and associated costs ≤4 weeks following positive COVID-19 test, stratified by age group, risk of severe COVID-19 and immunocompromised status.Results Among the hospitalised cohort, average length of stay, including critical care stays, was longer in older adults. Median healthcare cost per hospitalisation was higher in those aged 75–84 (£8942) and ≥85 years (£8835) than in those aged <50 years (£7703). While few (6.0%) patients in critical care required mechanical ventilation, its use was higher in older adults (50–74 years: 8.3%; <50 years: 4.3%). HCRU and associated costs were often greater in those at higher risk of severe COVID-19 than in the overall cohort, although minimal differences in HCRU were found across the three different high-risk definitions. Among the primary care cohort, general practitioner or nurse consultations were more frequent among older adults and the immunocompromised.Conclusions COVID-19-related hospitalisations in older adults, particularly critical care stays, were the primary drivers of high COVID-19 resource use in England. These findings may inform health policy decisions and resource allocation in the prevention and management of COVID-19. |
| first_indexed | 2024-03-08T18:02:55Z |
| format | Article |
| id | doaj.art-faf1104d26b6439298535c32194f0ae3 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-08T18:02:55Z |
| publishDate | 2023-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-faf1104d26b6439298535c32194f0ae32024-01-02T00:25:08ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-075495Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort studyCarmen Tsang0Robert Wood1Tendai Mugwagwa2Kiran K Rai3Jingyan Yang4Theo Tritton5Jennifer L Nguyen6Kathleen Michelle Andersen7Maya Reimbaeva8Leah J McGrath9Poppy Payne10Bethany Emma Backhouse11Diana Mendes12Rebecca Butfield13Kevin Naicker14Mary Araghi15Pfizer, Tadworth, UKAdelphi Real World, Bollington, UK1 Modelling and Economics Unit, National Infection Service, Public Health England, London, UK1 Institute of Applied Health Research, University of Birmingham, Birmingham, UKThe Institute for Social and Economic Research and Policy, Columbia University, New York, New York, USAAdelphi Real World, Bollington, UKDepartment of Urology, Hackensack Meridian Hackensack University Medical Center, Hackensack, New Jersey, USAPfizer Inc, New York, New York, USAPfizer Inc, New York, New York, USAPfizer Inc, New York, New York, USAAdelphi Real World, Bollington, UKAdelphi Real World, Bollington, UKPfizer, Tadworth, UKPfizer, Tadworth, UKPfizer, Tadworth, UKPfizer, Tadworth, UKObjectives To quantify direct costs and healthcare resource utilisation (HCRU) associated with acute COVID-19 in adults in England.Design Population-based retrospective cohort study using Clinical Practice Research Datalink Aurum primary care electronic medical records linked to Hospital Episode Statistics secondary care administrative data.Setting Patients registered to primary care practices in England.Population 1 706 368 adults with a positive SARS-CoV-2 PCR or antigen test from August 2020 to January 2022 were included; 13 105 within the hospitalised cohort indexed between August 2020 and March 2021, and 1 693 263 within the primary care cohort indexed between August 2020 and January 2022. Patients with a COVID-19-related hospitalisation within 84 days of a positive test were included in the hospitalised cohort.Main outcome measures Primary and secondary care HCRU and associated costs ≤4 weeks following positive COVID-19 test, stratified by age group, risk of severe COVID-19 and immunocompromised status.Results Among the hospitalised cohort, average length of stay, including critical care stays, was longer in older adults. Median healthcare cost per hospitalisation was higher in those aged 75–84 (£8942) and ≥85 years (£8835) than in those aged <50 years (£7703). While few (6.0%) patients in critical care required mechanical ventilation, its use was higher in older adults (50–74 years: 8.3%; <50 years: 4.3%). HCRU and associated costs were often greater in those at higher risk of severe COVID-19 than in the overall cohort, although minimal differences in HCRU were found across the three different high-risk definitions. Among the primary care cohort, general practitioner or nurse consultations were more frequent among older adults and the immunocompromised.Conclusions COVID-19-related hospitalisations in older adults, particularly critical care stays, were the primary drivers of high COVID-19 resource use in England. These findings may inform health policy decisions and resource allocation in the prevention and management of COVID-19.https://bmjopen.bmj.com/content/13/12/e075495.full |
| spellingShingle | Carmen Tsang Robert Wood Tendai Mugwagwa Kiran K Rai Jingyan Yang Theo Tritton Jennifer L Nguyen Kathleen Michelle Andersen Maya Reimbaeva Leah J McGrath Poppy Payne Bethany Emma Backhouse Diana Mendes Rebecca Butfield Kevin Naicker Mary Araghi Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study BMJ Open |
| title | Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study |
| title_full | Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study |
| title_fullStr | Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study |
| title_full_unstemmed | Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study |
| title_short | Healthcare resource utilisation and costs of hospitalisation and primary care among adults with COVID-19 in England: a population-based cohort study |
| title_sort | healthcare resource utilisation and costs of hospitalisation and primary care among adults with covid 19 in england a population based cohort study |
| url | https://bmjopen.bmj.com/content/13/12/e075495.full |
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