Early life swimming pool exposure and asthma onset in children – a case-control study
Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with...
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| Format: | Article |
| Language: | English |
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BMC
2018-04-01
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| Series: | Environmental Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12940-018-0383-0 |
| _version_ | 1819035493339234304 |
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| author | Martin Andersson Helena Backman Gunnar Nordberg Annika Hagenbjörk Linnea Hedman Kåre Eriksson Bertil Forsberg Eva Rönmark |
| author_facet | Martin Andersson Helena Backman Gunnar Nordberg Annika Hagenbjörk Linnea Hedman Kåre Eriksson Bertil Forsberg Eva Rönmark |
| author_sort | Martin Andersson |
| collection | DOAJ |
| description | Abstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16–17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews. Trichloramine concentrations in the pool buildings were measured. Skin prick test results for inhalant allergens were available from previous examinations of the cohort. The risk for asthma was analyzed in relation to the cumulative trichloramine exposure before onset of asthma. Results The participation rate was high in the original cohort (88 to 96%), and in the case-control study (80%). Trichloramine concentrations ranged from 0.020 to 0.55 mg/m3 (mean 0.15 mg/m3). Swimming pool exposure in early life was associated with a significantly higher risk of pre-school asthma onset. A dose-response relationship between swimming pool exposure and asthma was indicated in children with asthma onset at 1 year of age. Children who were both sensitized and exposed had a particularly high risk. Conclusions Early life exposure to chlorinated swimming pool environments was associated with pre-school asthma onset. |
| first_indexed | 2024-12-21T07:50:30Z |
| format | Article |
| id | doaj.art-faf48196781240d58e3e0ffc365ec8b8 |
| institution | Directory Open Access Journal |
| issn | 1476-069X |
| language | English |
| last_indexed | 2024-12-21T07:50:30Z |
| publishDate | 2018-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Environmental Health |
| spelling | doaj.art-faf48196781240d58e3e0ffc365ec8b82022-12-21T19:11:06ZengBMCEnvironmental Health1476-069X2018-04-0117111010.1186/s12940-018-0383-0Early life swimming pool exposure and asthma onset in children – a case-control studyMartin Andersson0Helena Backman1Gunnar Nordberg2Annika Hagenbjörk3Linnea Hedman4Kåre Eriksson5Bertil Forsberg6Eva Rönmark7Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityDepartment of Public Health and Clinical Medicine, Occupational and Environmental Medicine, Umeå UniversityAbstract Background Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure. Methods A longitudinal nested case-control study of 337 children with asthma (cases) and 633 controls aged 16–17 years was performed within a population-based cohort from The Obstructive Lung Disease in Northern Sweden studies (OLIN). Year of asthma onset and exposure time at different ages were obtained in telephone interviews. Trichloramine concentrations in the pool buildings were measured. Skin prick test results for inhalant allergens were available from previous examinations of the cohort. The risk for asthma was analyzed in relation to the cumulative trichloramine exposure before onset of asthma. Results The participation rate was high in the original cohort (88 to 96%), and in the case-control study (80%). Trichloramine concentrations ranged from 0.020 to 0.55 mg/m3 (mean 0.15 mg/m3). Swimming pool exposure in early life was associated with a significantly higher risk of pre-school asthma onset. A dose-response relationship between swimming pool exposure and asthma was indicated in children with asthma onset at 1 year of age. Children who were both sensitized and exposed had a particularly high risk. Conclusions Early life exposure to chlorinated swimming pool environments was associated with pre-school asthma onset.http://link.springer.com/article/10.1186/s12940-018-0383-0AsthmaTrichloramineChildrenSwimming |
| spellingShingle | Martin Andersson Helena Backman Gunnar Nordberg Annika Hagenbjörk Linnea Hedman Kåre Eriksson Bertil Forsberg Eva Rönmark Early life swimming pool exposure and asthma onset in children – a case-control study Environmental Health Asthma Trichloramine Children Swimming |
| title | Early life swimming pool exposure and asthma onset in children – a case-control study |
| title_full | Early life swimming pool exposure and asthma onset in children – a case-control study |
| title_fullStr | Early life swimming pool exposure and asthma onset in children – a case-control study |
| title_full_unstemmed | Early life swimming pool exposure and asthma onset in children – a case-control study |
| title_short | Early life swimming pool exposure and asthma onset in children – a case-control study |
| title_sort | early life swimming pool exposure and asthma onset in children a case control study |
| topic | Asthma Trichloramine Children Swimming |
| url | http://link.springer.com/article/10.1186/s12940-018-0383-0 |
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