MiR-200b is upregulated in plasma-derived exosomes and functions as an oncogene by promoting macrophage M2 polarization in ovarian cancer

MiR-200b is upregulated in plasma-derived exosomes and functions as an oncogene by promoting macrophage M2 polarization in ovarian cancer

Abstract Background Ovarian cancer is the seventh most common cancer in women and the second most reason of gynecologic cancer-related death. Growing evidence showed that exosomal miRNA plays a crucial role in the progression of ovarian cancer. Methods Exosomes were identified using nanoparticle tra...

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Bibliographic Details
Main Authors: Jun Xiong, Xiaoju He, Yuanyuan Xu, Wei Zhang, Fen Fu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
MiR-200b
Macrophage polarization
Kruppel like factor 6
Online Access:https://doi.org/10.1186/s13048-021-00826-9

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