Function and Therapeutic Implications of tRNA Derived Small RNAs

Function and Therapeutic Implications of tRNA Derived Small RNAs

tRNA derived small RNAs are mainly composed of tRNA fragments (tRFs) and tRNA halves (tiRs). Several functions have been attributed to tRFs and tiRs since their initial characterizations, spanning all aspects of regulation of the Central Dogma: from nascent RNA silencing, to post-transcriptional gen...

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Bibliographic Details
Main Authors: Briana Wilson, Anindya Dutta
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
tRNA fragments
RNA therapeutics
translation inhibition
post-transcriptional regulation of gene expression
RNA silencing
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.888424/full

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