Analysis of Compositional Bias in a Commercial Phage Display Peptide Library by Next-Generation Sequencing

The principal presumption of phage display biopanning is that the naïve library contains an unbiased repertoire of peptides, and thus, the enriched variants derive from the affinity selection of an entirely random peptide pool. In the current study, we utilized deep sequencing to characterize the wi...

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Hlavní autoři: Ane Beth Sloth, Babak Bakhshinejad, Malte Jensen, Camilla Stavnsbjerg, Mikkel Baldtzer Liisberg, Maria Rossing, Andreas Kjaer
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2022-10-01
Edice:Viruses
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On-line přístup:https://www.mdpi.com/1999-4915/14/11/2402