Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease
The CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease.
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2014-12-01
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| Series: | Balkan Journal of Medical Genetics |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/bjmg-2014-0072 |
| _version_ | 1797705361408393216 |
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| author | Sen H. M. Silan F. Degirmenci Y. Kamaran Ozisik H. I. |
| author_facet | Sen H. M. Silan F. Degirmenci Y. Kamaran Ozisik H. I. |
| author_sort | Sen H. M. |
| collection | DOAJ |
| description | The CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease. |
| first_indexed | 2024-03-12T05:35:00Z |
| format | Article |
| id | doaj.art-fafea0486724460cb918538fe68b1c4e |
| institution | Directory Open Access Journal |
| issn | 1311-0160 |
| language | English |
| last_indexed | 2024-03-12T05:35:00Z |
| publishDate | 2014-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Balkan Journal of Medical Genetics |
| spelling | doaj.art-fafea0486724460cb918538fe68b1c4e2023-09-03T06:32:19ZengSciendoBalkan Journal of Medical Genetics1311-01602014-12-01172374110.2478/bjmg-2014-0072bjmg-2014-0072Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular DiseaseSen H. M.0Silan F.1Degirmenci Y.2Kamaran Ozisik H. I.3Department of Neurology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Barboros Mah., Terzioğlu Kampüsü, Tıp Fakültesi, Çanakkale, Turkey. Tel : +90-286-218-37-38. Fax : +90-286-218-00-18.Department of Medical Genetics, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, TurkeyDepartment of Pharmacology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, TurkeyDepartment of Neurology, School of Medicine, Çanakkale Onsekiz Mart Üniversity, Çanakkale, TurkeyThe CY2C19 and P2Y12 gene polymorphisms are responsible for resistance to clopidogrel, known as drug unresponsiveness. In this study we researched the effect of gene polymorphism on clinical results of patients who began clopidogrel therapy after acute ischemic cerebrovascular disease.https://doi.org/10.2478/bjmg-2014-0072ischemic cerebrovascular disease (icvd)clopidogrelcyp2c19 and p2y12 gene polymorphisms |
| spellingShingle | Sen H. M. Silan F. Degirmenci Y. Kamaran Ozisik H. I. Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease Balkan Journal of Medical Genetics ischemic cerebrovascular disease (icvd) clopidogrel cyp2c19 and p2y12 gene polymorphisms |
| title | Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease |
| title_full | Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease |
| title_fullStr | Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease |
| title_full_unstemmed | Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease |
| title_short | Effects of Cyp2c19 and P2y12 Gene Polymorphisms on Clinical Results of Patients Using Clopidogrel After Acute Ischemic Cerebrovascular Disease |
| title_sort | effects of cyp2c19 and p2y12 gene polymorphisms on clinical results of patients using clopidogrel after acute ischemic cerebrovascular disease |
| topic | ischemic cerebrovascular disease (icvd) clopidogrel cyp2c19 and p2y12 gene polymorphisms |
| url | https://doi.org/10.2478/bjmg-2014-0072 |
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