Structural characterization of NrnC identifies unifying features of dinucleases

RNA degradation is fundamental for cellular homeostasis. The process is carried out by various classes of endolytic and exolytic enzymes that together degrade an RNA polymer to mono-ribonucleotides. Within the exoribonucleases, nano-RNases play a unique role as they act on the smallest breakdown pro...

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Hlavní autoři: Justin D Lormand, Soo-Kyoung Kim, George A Walters-Marrah, Bryce A Brownfield, J Christopher Fromme, Wade C Winkler, Jonathan R Goodson, Vincent T Lee, Holger Sondermann
Médium: Článek
Jazyk:English
Vydáno: eLife Sciences Publications Ltd 2021-09-01
Edice:eLife
Témata:
On-line přístup:https://elifesciences.org/articles/70146