COVID-19 during Early Phase of Autologous Stem Cell Transplantation

COVID-19 during Early Phase of Autologous Stem Cell Transplantation

We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our r...

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Bibliographic Details
Main Authors: Sławomir Milczarek, Bartłomiej Baumert, Anna Sobuś, Ewa Wilk-Milczarek, Krzysztof Sommerfeld, Bogumiła Osękowska, Ewa Borowiecka, Edyta Paczkowska, Aleksandra Łanocha, Wojciech Poncyliusz, Konrad Jarosz, Bogusław Machaliński
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Medicina
Subjects:
COVID-19
AHSCT
lymphoblastic lymphoma
chemotherapy
Online Access:https://www.mdpi.com/1648-9144/57/7/724
Description
Summary:We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our report emphasizes the need to investigate whether timely steroid therapy upon neutrophil engraftment in the setting of COVID-19 could limit the extent of lung injury and prevent ARDS. Furthermore, we discuss a significant issue of possible prolonged incubation of the virus in heavily pretreated hematological patients.
ISSN:1010-660X
1648-9144

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