COVID-19 during Early Phase of Autologous Stem Cell Transplantation
We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our r...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/57/7/724 |
| _version_ | 1797526693430165504 |
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| author | Sławomir Milczarek Bartłomiej Baumert Anna Sobuś Ewa Wilk-Milczarek Krzysztof Sommerfeld Bogumiła Osękowska Ewa Borowiecka Edyta Paczkowska Aleksandra Łanocha Wojciech Poncyliusz Konrad Jarosz Bogusław Machaliński |
| author_facet | Sławomir Milczarek Bartłomiej Baumert Anna Sobuś Ewa Wilk-Milczarek Krzysztof Sommerfeld Bogumiła Osękowska Ewa Borowiecka Edyta Paczkowska Aleksandra Łanocha Wojciech Poncyliusz Konrad Jarosz Bogusław Machaliński |
| author_sort | Sławomir Milczarek |
| collection | DOAJ |
| description | We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our report emphasizes the need to investigate whether timely steroid therapy upon neutrophil engraftment in the setting of COVID-19 could limit the extent of lung injury and prevent ARDS. Furthermore, we discuss a significant issue of possible prolonged incubation of the virus in heavily pretreated hematological patients. |
| first_indexed | 2024-03-10T09:32:59Z |
| format | Article |
| id | doaj.art-fb006c8f92964167a35a20ff8028133f |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T09:32:59Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-fb006c8f92964167a35a20ff8028133f2023-11-22T04:21:45ZengMDPI AGMedicina1010-660X1648-91442021-07-0157772410.3390/medicina57070724COVID-19 during Early Phase of Autologous Stem Cell TransplantationSławomir Milczarek0Bartłomiej Baumert1Anna Sobuś2Ewa Wilk-Milczarek3Krzysztof Sommerfeld4Bogumiła Osękowska5Ewa Borowiecka6Edyta Paczkowska7Aleksandra Łanocha8Wojciech Poncyliusz9Konrad Jarosz10Bogusław Machaliński11Department of General Pathology, Pomeranian Medical University, 70-111 Szczecin, PolandDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, PolandDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, PolandDepartment of General and Dental Radiology, Pomeranian Medical University, 70-111 Szczecin, PolandDepartment of Hematology and Transplantology, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of Hematology and Transplantology, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of Hematology and Transplantology, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, PolandDepartment of Hematology and Transplantology, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of Anaesthesiology and Intensive Care, Pomeranian Medical University, 71-252 Szczecin, PolandDepartment of General Pathology, Pomeranian Medical University, 70-111 Szczecin, PolandWe present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that cannot be assigned to engraftment syndrome. Our report emphasizes the need to investigate whether timely steroid therapy upon neutrophil engraftment in the setting of COVID-19 could limit the extent of lung injury and prevent ARDS. Furthermore, we discuss a significant issue of possible prolonged incubation of the virus in heavily pretreated hematological patients.https://www.mdpi.com/1648-9144/57/7/724COVID-19AHSCTlymphoblastic lymphomachemotherapy |
| spellingShingle | Sławomir Milczarek Bartłomiej Baumert Anna Sobuś Ewa Wilk-Milczarek Krzysztof Sommerfeld Bogumiła Osękowska Ewa Borowiecka Edyta Paczkowska Aleksandra Łanocha Wojciech Poncyliusz Konrad Jarosz Bogusław Machaliński COVID-19 during Early Phase of Autologous Stem Cell Transplantation Medicina COVID-19 AHSCT lymphoblastic lymphoma chemotherapy |
| title | COVID-19 during Early Phase of Autologous Stem Cell Transplantation |
| title_full | COVID-19 during Early Phase of Autologous Stem Cell Transplantation |
| title_fullStr | COVID-19 during Early Phase of Autologous Stem Cell Transplantation |
| title_full_unstemmed | COVID-19 during Early Phase of Autologous Stem Cell Transplantation |
| title_short | COVID-19 during Early Phase of Autologous Stem Cell Transplantation |
| title_sort | covid 19 during early phase of autologous stem cell transplantation |
| topic | COVID-19 AHSCT lymphoblastic lymphoma chemotherapy |
| url | https://www.mdpi.com/1648-9144/57/7/724 |
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