Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy
Fritillaria has a long history in China, and it can be consumed as medicine and food. Owing to the high cost of Fritillaria cirrhosa, traders sometimes mix it with the cheaper Fritillaria thunbergii powder to make profit. Herein, we proposed a laser-induced breakdown spectroscopy (LIBS) technique to...
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MDPI AG
2023-04-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/12/8/1710 |
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| author | Kai Wei Geer Teng Qianqian Wang Xiangjun Xu Zhifang Zhao Haida Liu Mengyu Bao Yongyue Zheng Tianzhong Luo Bingheng Lu |
| author_facet | Kai Wei Geer Teng Qianqian Wang Xiangjun Xu Zhifang Zhao Haida Liu Mengyu Bao Yongyue Zheng Tianzhong Luo Bingheng Lu |
| author_sort | Kai Wei |
| collection | DOAJ |
| description | Fritillaria has a long history in China, and it can be consumed as medicine and food. Owing to the high cost of Fritillaria cirrhosa, traders sometimes mix it with the cheaper Fritillaria thunbergii powder to make profit. Herein, we proposed a laser-induced breakdown spectroscopy (LIBS) technique to test the adulteration present in the sample of Fritillaria cirrhosa powder. Experimental samples with different adulteration levels were prepared, and their LIBS spectra were obtained. Partial least squares regression (PLSR) was adopted as the quantitative analysis model to compare the effects of four data standardization methods, namely, mean centring, normalization by total area, standard normal variable, and normalization by the maximum, on the performance of the PLSR model. Principal component analysis and least absolute shrinkage and selection operator (LASSO) were utilized for feature extraction and feature selection, and the performance of the PLSR model was determined based on its quantitative analysis. Subsequently, the optimal number of features was determined. The residuals were corrected using support vector regression (SVR). The mean absolute error and root mean square error of prediction obtained from the quantitative analysis results of the combined LASSO-PLSR-SVR model for the test set data were 5.0396% and 7.2491%, respectively, and the coefficient of determination R<sup>2</sup> was 0.9983. The results showed that the LIBS technique can be adopted to test adulteration in the sample of Fritillaria cirrhosa powder and has potential applications in drug quality control. |
| first_indexed | 2024-03-11T05:01:41Z |
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| id | doaj.art-fb01c107a5b1460f926ac15db120cb0e |
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| language | English |
| last_indexed | 2024-03-11T05:01:41Z |
| publishDate | 2023-04-01 |
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| series | Foods |
| spelling | doaj.art-fb01c107a5b1460f926ac15db120cb0e2023-11-17T19:15:35ZengMDPI AGFoods2304-81582023-04-01128171010.3390/foods12081710Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown SpectroscopyKai Wei0Geer Teng1Qianqian Wang2Xiangjun Xu3Zhifang Zhao4Haida Liu5Mengyu Bao6Yongyue Zheng7Tianzhong Luo8Bingheng Lu9School of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaSchool of Optics and Photonics, Beijing Institute of Technology, Beijing 100081, ChinaFritillaria has a long history in China, and it can be consumed as medicine and food. Owing to the high cost of Fritillaria cirrhosa, traders sometimes mix it with the cheaper Fritillaria thunbergii powder to make profit. Herein, we proposed a laser-induced breakdown spectroscopy (LIBS) technique to test the adulteration present in the sample of Fritillaria cirrhosa powder. Experimental samples with different adulteration levels were prepared, and their LIBS spectra were obtained. Partial least squares regression (PLSR) was adopted as the quantitative analysis model to compare the effects of four data standardization methods, namely, mean centring, normalization by total area, standard normal variable, and normalization by the maximum, on the performance of the PLSR model. Principal component analysis and least absolute shrinkage and selection operator (LASSO) were utilized for feature extraction and feature selection, and the performance of the PLSR model was determined based on its quantitative analysis. Subsequently, the optimal number of features was determined. The residuals were corrected using support vector regression (SVR). The mean absolute error and root mean square error of prediction obtained from the quantitative analysis results of the combined LASSO-PLSR-SVR model for the test set data were 5.0396% and 7.2491%, respectively, and the coefficient of determination R<sup>2</sup> was 0.9983. The results showed that the LIBS technique can be adopted to test adulteration in the sample of Fritillaria cirrhosa powder and has potential applications in drug quality control.https://www.mdpi.com/2304-8158/12/8/1710Laser-induced breakdown spectroscopyquantitative analysischemometric methods |
| spellingShingle | Kai Wei Geer Teng Qianqian Wang Xiangjun Xu Zhifang Zhao Haida Liu Mengyu Bao Yongyue Zheng Tianzhong Luo Bingheng Lu Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy Foods Laser-induced breakdown spectroscopy quantitative analysis chemometric methods |
| title | Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy |
| title_full | Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy |
| title_fullStr | Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy |
| title_full_unstemmed | Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy |
| title_short | Rapid Test for Adulteration of Fritillaria Thunbergii in Fritillaria Cirrhosa by Laser-Induced Breakdown Spectroscopy |
| title_sort | rapid test for adulteration of fritillaria thunbergii in fritillaria cirrhosa by laser induced breakdown spectroscopy |
| topic | Laser-induced breakdown spectroscopy quantitative analysis chemometric methods |
| url | https://www.mdpi.com/2304-8158/12/8/1710 |
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