New binary solid dispersion of indomethacin and croscarmellose sodium: physical characterization and in vitro dissolution enhancement

New binary solid dispersion of indomethacin and croscarmellose sodium: physical characterization and in vitro dissolution enhancement

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Solid dispersions (SDx) containing Indomethacin (IND), a poorly water-soluble drug, and the disintegrant excipient sodium croscarmellose (SC) were prepared by a co-drying method and characterized by Infrared spectroscopy (FT-IR), X-ray diffraction (XRD), differential scanning calorimetry (DSC) and s...

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Bibliographic Details
Main Authors:	Silvina G. Castro, María V. Ramírez-Rigo, Daniel A. Allemandi, Santiago D. Palma
Format:	Article
Language:	English
Published:	International Pharmaceutical Excipients Council 2016-11-01
Series:	Journal of Excipients and Food Chemicals
Online Access:	https://jefc.scholasticahq.com/article/1101-new-binary-solid-dispersion-of-indomethacin-and-croscarmellose-sodium-physical-characterization-and-in-vitro-dissolution-enhancement

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