Bridging the translational gap: adenosine as a modulator of neuropathic pain in preclinical models and humans

This review aims to analyse the published data on preclinical and human experimental and clinical adenosine modulation for pain management. We summarise the translatability of the adenosine pathway for further drug development and aim to reveal subgroups of pain patients that could benefit from targ...

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Bibliographic Details
Main Authors: Arendt-Nielsen Lars, Klitgaard Henrik, Hansen Stine N.
Format: Article
Language:English
Published: De Gruyter 2023-12-01
Series:Scandinavian Journal of Pain
Subjects:
Online Access:https://doi.org/10.1515/sjpain-2023-0048
Description
Summary:This review aims to analyse the published data on preclinical and human experimental and clinical adenosine modulation for pain management. We summarise the translatability of the adenosine pathway for further drug development and aim to reveal subgroups of pain patients that could benefit from targeting the pathway.
ISSN:1877-8860
1877-8879