A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome

This case report describes a 46-year-old female with a history of multiple endocrine neoplasia type 1 syndrome status post-parathyroidectomy, thymectomy via robotic video-assisted thoracoscopic surgery, and pituitary adenoma resection presenting with parasympathetic hyperactivity and Parry–Romberg s...

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Main Authors: Andrea N Clapp, Anna DePold Hohler
Format: Article
Language:English
Published: SAGE Publishing 2021-07-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X211034351
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author Andrea N Clapp
Anna DePold Hohler
author_facet Andrea N Clapp
Anna DePold Hohler
author_sort Andrea N Clapp
collection DOAJ
description This case report describes a 46-year-old female with a history of multiple endocrine neoplasia type 1 syndrome status post-parathyroidectomy, thymectomy via robotic video-assisted thoracoscopic surgery, and pituitary adenoma resection presenting with parasympathetic hyperactivity and Parry–Romberg syndrome. Parry–Romberg syndrome is a rare disorder that manifests as facial hemiatrophy. Reported symptoms include cognitive dysfunction, olfactory hallucinations, and parasympathetic hyperactivity: miosis of the right eye, anhidrosis, diarrhea, urinary incontinence, bowel incontinence, and orthostatic hypotension. Previous reports have noted associations between Parry–Romberg syndrome and sympathetic hyperactivity and dysregulation. This case report focuses on an association between Parry–Romberg syndrome and unopposed parasympathetic activity.
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spelling doaj.art-fb06602059a9404b8bacad428c39cb8a2022-12-21T18:27:36ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2021-07-01910.1177/2050313X211034351A case of parasympathetic hyperactivity and associated Parry–Romberg syndromeAndrea N Clapp0Anna DePold Hohler1Tufts University School of Medicine, Boston, MA, USADepartment of Neurology, St. Elizabeth’s Medical Center, Brighton, MA, USAThis case report describes a 46-year-old female with a history of multiple endocrine neoplasia type 1 syndrome status post-parathyroidectomy, thymectomy via robotic video-assisted thoracoscopic surgery, and pituitary adenoma resection presenting with parasympathetic hyperactivity and Parry–Romberg syndrome. Parry–Romberg syndrome is a rare disorder that manifests as facial hemiatrophy. Reported symptoms include cognitive dysfunction, olfactory hallucinations, and parasympathetic hyperactivity: miosis of the right eye, anhidrosis, diarrhea, urinary incontinence, bowel incontinence, and orthostatic hypotension. Previous reports have noted associations between Parry–Romberg syndrome and sympathetic hyperactivity and dysregulation. This case report focuses on an association between Parry–Romberg syndrome and unopposed parasympathetic activity.https://doi.org/10.1177/2050313X211034351
spellingShingle Andrea N Clapp
Anna DePold Hohler
A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
SAGE Open Medical Case Reports
title A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
title_full A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
title_fullStr A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
title_full_unstemmed A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
title_short A case of parasympathetic hyperactivity and associated Parry–Romberg syndrome
title_sort case of parasympathetic hyperactivity and associated parry romberg syndrome
url https://doi.org/10.1177/2050313X211034351
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