Partial splenic embolization for refractory thrombocytopenia

When the platelet count falls below 20¥ 109/L, the risk of spontaneous life threatening hemorrhage is concerning for both physician and patient. When medical management fails, splenectomy is often used to manage the severe thrombocytopenia before spontaneous, life-threatening gastrointestinal or int...

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Bibliographic Details
Main Author: Irwin M. Best
Format: Article
Language:English
Published: MDPI AG 2011-12-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.clinicsandpractice.org/index.php/cp/article/view/248
Description
Summary:When the platelet count falls below 20¥ 109/L, the risk of spontaneous life threatening hemorrhage is concerning for both physician and patient. When medical management fails, splenectomy is often used to manage the severe thrombocytopenia before spontaneous, life-threatening gastrointestinal or intracranial bleeding occurs. We present the non surgical management of such a patient with refractory sever thrombocytopenia who refused surgical intervention. She underwent partial splenic embolic therapy with 500-700 ? particles. Her platelet count spontaneous recovered from less than 20¥109/L to normal range. Her counts remained in normal range after discharge home. Further study is needed to determine the most appropriate role for embolization in patients who are refractory to medical management and those with chronically low platelet counts requiring frequent plate transfusions for invasive procedures.
ISSN:2039-7275
2039-7283