Analysis of Fragmentation Pathways of Peptide Modified with Quaternary Ammonium and Phosphonium Group as Ionization Enhancers

Analysis of Fragmentation Pathways of Peptide Modified with Quaternary Ammonium and Phosphonium Group as Ionization Enhancers

Peptide modification by a quaternary ammonium group containing a permanent positive charge is a promising method of increasing the ionization efficiency of the analyzed compounds, making ultra-sensitive detection even at the attomolar level possible. Charge-derivatized peptides may undergo both char...

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Bibliographic Details
Main Authors: Monika Kijewska, Dorota Gąszczyk, Remigiusz Bąchor, Piotr Stefanowicz, Zbigniew Szewczuk
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
derivatization
fixed charge tag
quaternary ammonium salt
mass spectrometry
electron-capture dissociation
collision induced dissociation
Online Access:https://www.mdpi.com/1420-3049/26/22/6964

Internet

https://www.mdpi.com/1420-3049/26/22/6964

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