Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice

Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice

Vitamin E, the most important lipophilic radical scavenging antioxidant in vivo, has a pivotal role in brain. In an earlier study, we observed that adult mice with a defect in the gene encoding plasma phospholipid transfer protein (PLTP) display a moderate reduction in cerebral vitamin E levels, and...

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Bibliographic Details
Main Authors: Catherine M. Desrumaux, Marine Mansuy, Stéphanie Lemaire, Justine Przybilski, Naig Le Guern, Laurent Givalois, Laurent Lagrost
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
vitamin E
lipid transfer
development
brain
glutamate
Online Access:https://www.frontiersin.org/article/10.3389/fnbeh.2018.00310/full

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