Ion Channel Modeling beyond State of the Art: A Comparison with a System Theory-Based Model of the Shaker-Related Voltage-Gated Potassium Channel Kv1.1

Ion Channel Modeling beyond State of the Art: A Comparison with a System Theory-Based Model of the Shaker-Related Voltage-Gated Potassium Channel Kv1.1

The mathematical modeling of ion channel kinetics is an important tool for studying the electrophysiological mechanisms of the nerves, heart, or cancer, from a single cell to an organ. Common approaches use either a Hodgkin–Huxley (HH) or a hidden Markov model (HMM) description, depending on the lev...

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Bibliographic Details
Main Authors: Sonja Langthaler, Jasmina Lozanović Šajić, Theresa Rienmüller, Seth H. Weinberg, Christian Baumgartner
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
ion channels
electrophysiology
computational model
Hodgkin–Huxley
hidden Markov model
system and control theory
Online Access:https://www.mdpi.com/2073-4409/11/2/239

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