The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles

Background&Objective: Up to seventh week of gestation, progesterone secreted from the ovary is necessary to preserve the pregnancy. In the ART cycles GnRH-a is prescribed and oocytes and granulosa cells or retrieved, both causes corpus luteum insufficiency, so corpus luteum should be supported t...

Full description

Bibliographic Details
Main Authors: S.Kadkhodayan (MD), F.Vahid-Roodsary (MD)
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2005-10-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-31&slc_lang=en&sid=1
_version_ 1811277046840557568
author S.Kadkhodayan (MD)
F.Vahid-Roodsary (MD)
author_facet S.Kadkhodayan (MD)
F.Vahid-Roodsary (MD)
author_sort S.Kadkhodayan (MD)
collection DOAJ
description Background&Objective: Up to seventh week of gestation, progesterone secreted from the ovary is necessary to preserve the pregnancy. In the ART cycles GnRH-a is prescribed and oocytes and granulosa cells or retrieved, both causes corpus luteum insufficiency, so corpus luteum should be supported the best way is progesterone prescription. In this research we compare intramuscular and intravaginal suppositoar forms of progesterone for preserve the pregnancy. Materials&Methods: A prospective cross sectional evaluation on 193 patients was designed. All of them were on IVF or ICSI cycles. The patients were randomly divided into two groups. Intramuscular progesterone was prescribed in 138 and intravaginal progesterone (supp cyclogest) in 54 patients. The outcome of pregnancy was analyzed using statistical trials including t-test and chi-squre. Results: The two groups were similar duo to age – the ethiology causes of infertility – the doses of proscribed HMG ampule – FSH titrago – the number and grade of transferred embryos. The day after HCG presciption until the end the seventh week in the first group (138 patients) intramuscular progestrone (50 mg /bid) and in the secound group (54 Patients) supp of cyclogest (400 mg / bid) was prescnbed. The rate of positive pregnancy test, abortion, successful poegnancy in this two groups were similar. Conclusion: Intramuscular or intravaginal progesterone for supporting corpus luteum in IVF or ICSI cycles has the same effect but the intramuscular route is cheaper.
first_indexed 2024-04-13T00:08:39Z
format Article
id doaj.art-fb160efcc3c14fc6862fe8d275f13794
institution Directory Open Access Journal
issn 1562-4765
2008-4080
language fas
last_indexed 2024-04-13T00:08:39Z
publishDate 2005-10-01
publisher Golestan University of Medical Sciences
record_format Article
series مجله دانشگاه علوم پزشکی گرگان
spelling doaj.art-fb160efcc3c14fc6862fe8d275f137942022-12-22T03:11:10ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802005-10-01722730The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cyclesS.Kadkhodayan (MD)0F.Vahid-Roodsary (MD)1 Background&Objective: Up to seventh week of gestation, progesterone secreted from the ovary is necessary to preserve the pregnancy. In the ART cycles GnRH-a is prescribed and oocytes and granulosa cells or retrieved, both causes corpus luteum insufficiency, so corpus luteum should be supported the best way is progesterone prescription. In this research we compare intramuscular and intravaginal suppositoar forms of progesterone for preserve the pregnancy. Materials&Methods: A prospective cross sectional evaluation on 193 patients was designed. All of them were on IVF or ICSI cycles. The patients were randomly divided into two groups. Intramuscular progesterone was prescribed in 138 and intravaginal progesterone (supp cyclogest) in 54 patients. The outcome of pregnancy was analyzed using statistical trials including t-test and chi-squre. Results: The two groups were similar duo to age – the ethiology causes of infertility – the doses of proscribed HMG ampule – FSH titrago – the number and grade of transferred embryos. The day after HCG presciption until the end the seventh week in the first group (138 patients) intramuscular progestrone (50 mg /bid) and in the secound group (54 Patients) supp of cyclogest (400 mg / bid) was prescnbed. The rate of positive pregnancy test, abortion, successful poegnancy in this two groups were similar. Conclusion: Intramuscular or intravaginal progesterone for supporting corpus luteum in IVF or ICSI cycles has the same effect but the intramuscular route is cheaper.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-31&slc_lang=en&sid=1Corpus Luteum SupportIVFICSIIntramuscular ProgesteroneIntravaginal Progesterone
spellingShingle S.Kadkhodayan (MD)
F.Vahid-Roodsary (MD)
The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
مجله دانشگاه علوم پزشکی گرگان
Corpus Luteum Support
IVF
ICSI
Intramuscular Progesterone
Intravaginal Progesterone
title The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
title_full The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
title_fullStr The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
title_full_unstemmed The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
title_short The comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the Luteum phase in ART cycles
title_sort comparasion of intramuscular and intravagnial suppositoar forms of progesterone for supporting the luteum phase in art cycles
topic Corpus Luteum Support
IVF
ICSI
Intramuscular Progesterone
Intravaginal Progesterone
url http://goums.ac.ir/journal/browse.php?a_code=A-10-1-31&slc_lang=en&sid=1
work_keys_str_mv AT skadkhodayanmd thecomparasionofintramuscularandintravagnialsuppositoarformsofprogesteroneforsupportingtheluteumphaseinartcycles
AT fvahidroodsarymd thecomparasionofintramuscularandintravagnialsuppositoarformsofprogesteroneforsupportingtheluteumphaseinartcycles
AT skadkhodayanmd comparasionofintramuscularandintravagnialsuppositoarformsofprogesteroneforsupportingtheluteumphaseinartcycles
AT fvahidroodsarymd comparasionofintramuscularandintravagnialsuppositoarformsofprogesteroneforsupportingtheluteumphaseinartcycles