Eda controls the size of the enamel knot during incisor development

Eda controls the size of the enamel knot during incisor development

Ectodysplasin (Eda) plays important roles in both shaping the developing tooth and establishing the number of teeth within the tooth row. Sonic hedgehog (Shh) has been shown to act downstream of Eda and is involved in the initiation of tooth development. Eda−/− mice possess hypoplastic and hypominer...

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Bibliographic Details
Main Authors: Lucie Horakova, Linda Dalecka, Oldrich Zahradnicek, Katerina Lochovska, Herve Lesot, Renata Peterkova, Abigail S. Tucker, Maria Hovorakova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Physiology
Subjects:
tabby mouse
mouse incisor
shh expression
rudiment
tooth development
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1033130/full

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