LMC y detección del gen de fusión BCR/ABL

LMC y detección del gen de fusión BCR/ABL

La anormalidad citogenética más común en la leucemia mieloide crónica (LMC) es el cromosoma Philadelphia producida por la translocación t(9:22), cuya expresión molecular es el gen de fusión BCR-ABL, que codifica una proteína con actividad tirosinquinasa.

Bibliographic Details
Main Author:	C. G. Artigas Allaire
Format:	Article
Language:	Spanish
Published:	Universidad de Antioquia 2006-04-01
Series:	Iatreia
Online Access:	http://www.iatreia.udea.edu.co/index.php/iatreia/article/view/1182

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