Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease

Silencing of FABP1 ameliorates hepatic steatosis, inflammation, and oxidative stress in mice with nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence worldwide and has been identified as a risk factor for cirrhosis and hepatocellular carcinoma. However, there is no effective pharmacologic treatment for NAFLD. FABP1 is a liver‐specific fatty acid‐binding protein (FABP) that plays...

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Bibliographic Details
Main Authors: Takako Mukai, Miki Egawa, Tamaki Takeuchi, Hitoshi Yamashita, Tatsuya Kusudo
Format: Article
Language:English
Published: Wiley 2017-07-01
Series:FEBS Open Bio
Subjects:
FABP1
NAFLD
Online Access:https://doi.org/10.1002/2211-5463.12240

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